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上呼吸道感染對(duì)嗅覺功能障礙患者的影響研究

發(fā)布時(shí)間:2019-02-10 20:03
【摘要】:目的探討上呼吸道感染對(duì)嗅覺功能障礙患者的影響,為臨床提供理論依據(jù)。方法選擇2010年1月-2015年6月在醫(yī)院就診的晚期喉癌或下咽癌術(shù)后咽瘺患者515例,作為研究組,選擇100名健康體檢者作為對(duì)照組,檢測(cè)兩組入選者嗅覺識(shí)別閾值分?jǐn)?shù)、嗅球體積、嗅溝深度。結(jié)果研究組患者中,31例發(fā)生上呼吸道感染,感染率為6.02%;上呼吸道感染患者嗅覺識(shí)別閾值分?jǐn)?shù)為(2.87±0.33)分,未感染患者嗅覺識(shí)別閾值分?jǐn)?shù)為(0.89±0.21)分(P0.05),對(duì)照組嗅球體積高于研究組,研究組未感染患者嗅球體積大于感染患者,差異有統(tǒng)計(jì)學(xué)意義(P0.05),兩組嗅溝深度比較差異無統(tǒng)計(jì)學(xué)意義。結(jié)論上呼吸道感染導(dǎo)致患者嗅球體積縮小,增加嗅覺識(shí)別閾值分?jǐn)?shù),降低患者的嗅覺功能。
[Abstract]:Objective to investigate the effect of upper respiratory tract infection on patients with olfactory dysfunction. Methods from January 2010 to June 2015, 515 patients with advanced laryngeal cancer or hypopharyngeal carcinoma after pharyngeal fistula were selected as study group and 100 healthy persons as control group. Olfactory recognition threshold scores were measured in both groups. Olfactory bulb volume, olfactory groove depth. Results in the study group, 31 cases had upper respiratory tract infection, and the infection rate was 6.02%. The olfactory recognition threshold score of upper respiratory tract infection patients was (2.87 鹵0.33), that of uninfected patients was (0.89 鹵0.21) (P0.05). The volume of olfactory bulb in the control group was higher than that in the study group. The volume of olfactory bulb in the study group was larger than that in the infected group (P0.05), and there was no significant difference in the depth of olfactory groove between the two groups. Conclusion the volume of olfactory bulb in patients with upper respiratory tract infection is reduced, the threshold of olfactory recognition is increased, and the olfactory function is decreased.
【作者單位】: 濟(jì)寧市第一人民醫(yī)院耳鼻喉科;濟(jì)寧口腔醫(yī)院兒童牙病科;
【基金】:山東省自然科學(xué)基金資助項(xiàng)目(Y2006C02)
【分類號(hào)】:R56;R765
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本文編號(hào):2419497

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