【摘要】：目的多元回歸分析重癥監(jiān)護(hù)病房(ICU)鮑氏不動桿菌(ABA)致呼吸機(jī)相關(guān)性肺炎的危險因素,制定相關(guān)干預(yù)對策。方法選擇2013年3月-2016年3月醫(yī)院ICU治療ABA致呼吸機(jī)相關(guān)性肺炎患者126例進(jìn)行研究,統(tǒng)計感染ABA的藥敏性,并分析ICU ABA致呼吸機(jī)相關(guān)性肺炎發(fā)生的危險因素,進(jìn)行統(tǒng)計分析。結(jié)果ABA對氨芐西林、慶大霉素的耐藥率較高達(dá)90.00%以上,對亞胺培南和美羅培南最為敏感,耐藥率均20.00%,其中85株ABA顯示對≥3種抗菌藥物耐藥為泛耐藥;單因素分析顯示,ICU泛耐藥ABA呼吸機(jī)相關(guān)性肺炎的發(fā)生與住院時間、機(jī)械通氣方式、使用糖皮質(zhì)激素、留置胃管、使用碳青霉烯類抗菌藥物及使用≥3種抗菌藥物呈明顯相關(guān)性(χ2=20.292、10.414、7.524、7.810、9.760和11.635,P0.05);logistic回歸模型分析顯示,機(jī)械通氣方式、留置胃管、使用≥3種抗菌藥物是ICU泛耐藥ABA呼吸機(jī)相關(guān)性肺炎發(fā)生的獨(dú)立危險因素(OR=6.527、6.337、5.467,P0.05)。結(jié)論 ICU呼吸機(jī)相關(guān)性肺炎ABA泛耐藥現(xiàn)象嚴(yán)重,機(jī)械通氣方式、留置胃管、使用≥3種抗菌藥物是其發(fā)生的獨(dú)立危險因素,醫(yī)護(hù)人員應(yīng)避免ABA感染和耐藥的進(jìn)一步傳播。
[Abstract]:Objective to analyze the risk factors of ventilator-associated pneumonia caused by Acinetobacter baumannii (ABA) in intensive care unit (ICU) by multiple regression analysis. Methods 126 patients with ventilator-associated pneumonia caused by ABA were treated with ICU from March 2013 to March 2016. The drug sensitivity of ABA infection was analyzed and the risk factors of ICU ABA induced ventilator-associated pneumonia were analyzed. Results the resistance rate of ABA to ampicillin and gentamicin was 90.00%, and was most sensitive to imipenem and meropenem, the resistance rate was 20.00%. 85 strains of ABA showed pan-resistance to more than 3 kinds of antimicrobial agents. Univariate analysis showed that ICU pan-resistant ABA ventilator-associated pneumonia was associated with duration of hospitalization, mechanical ventilation, use of glucocorticoid, indwelling of gastric tube, There was a significant correlation between carbapenes and 鈮，

本文編號：2390616