【摘要】：目的評價結核感染T細胞斑點試驗(T-SPOT.TB)診斷艾滋病合并肺結核的臨床應用價值,以利于疾病診斷與鑒別診斷。方法選取45例合并肺結核的艾滋病患者(研究組)及30例未感染肺結核的艾滋病患者(對照組)行T-SPOT.TB檢測,并同時行結核菌素純蛋白衍生物(PPD)試驗。結果研究組T-SPOT.TB陽性率為80.0%,顯著高于對照組13.3%(χ2=32.14,P0.01),PPD試驗在兩組間的陽性率分別為13.3%和6.7%;研究組CD4+T細胞計數(shù)≥200/μl及200/μl的患者中T-SPOT.TB檢測陽性率分別為86.7%和76.7%,差異無統(tǒng)計學意義;T-SPOT.TB檢測艾滋病合并肺結核的敏感性為80.0%、特異性為76.7%,陽性似然比6.0,陰性似然比0.1;在PPD試驗中分別為13.3%、93.3%、2.0、0.9。結論 T-SPOT.TB對艾滋病合并肺結核具有較高的診斷效能。
[Abstract]:Objective to evaluate the clinical value of T cell spot test (T-SPOT.TB) in the diagnosis of AIDS complicated with pulmonary tuberculosis. Methods T-SPOT.TB was detected in 45 AIDS patients with pulmonary tuberculosis (study group) and 30 AIDS patients without pulmonary tuberculosis (control group), and the PPD test was performed at the same time. Results the positive rate of T-SPOT.TB in the study group was 80.0, which was significantly higher than that in the control group (13.3%) (蠂 ~ (2) 2) (32.14 / P0.01). The positive rates of T-SPOT.TB in the study group were 13.3% and 6.7%, respectively, and the positive rates of T-SPOT.TB were 86.7% and 76.77% in the patients with CD4 T cell count 鈮，

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