發(fā)布時間：2018-06-24 20:16

  本文選題：系統(tǒng)性紅斑狼瘡 + 狼瘡性肺炎�。� 參考：《中國呼吸與危重監(jiān)護(hù)雜志》2017年06期

【摘要】：目的 探討系統(tǒng)性紅斑狼瘡(systemic lupus erythematosus,SLE)繼發(fā)氣胸的臨床特征,增加對其的認(rèn)識。方法 對1例SLE患者發(fā)生急性狼瘡性肺炎繼發(fā)氣胸的發(fā)病過程、臨床表現(xiàn)、胸部影像學(xué)特點(diǎn)及診治經(jīng)過進(jìn)行分析。以"systemic lupus erythematosus"和"pneumothorax"為檢索詞在PubMed數(shù)據(jù)庫進(jìn)行檢索,以"狼瘡"和"氣胸"為檢索詞在萬方數(shù)據(jù)庫和中國知網(wǎng)數(shù)據(jù)庫中進(jìn)行檢索,檢索時間為1971~2016年,復(fù)習(xí)相關(guān)文獻(xiàn)。結(jié)果 患者,女,26歲,因反復(fù)發(fā)熱3個月,胸悶、氣促10 d于2016年12月就診。診斷為急性狼瘡性肺炎。入院后接受糖皮質(zhì)激素、環(huán)磷酰胺及血漿置換等治療。住院期間患者突發(fā)右側(cè)胸痛,胸部CT檢查提示右側(cè)氣胸,經(jīng)胸腔閉式引流后好轉(zhuǎn)。檢索文獻(xiàn)報道14例,其中2例因數(shù)據(jù)不全被剔除。余下的12例中女9例,男3例。平均年齡(28.0±11.9)歲。其臨床表現(xiàn)多為突發(fā)胸悶、氣促,常伴有胸膜下肺空洞、囊腔狀改變。大部分患者經(jīng)胸腔閉式引流后氣胸消失,少數(shù)需接受胸腔鏡手術(shù)。結(jié)論 SLE繼發(fā)氣胸罕見,常與SLE繼發(fā)肺空洞、囊腔破裂有關(guān),大部分患者經(jīng)胸腔閉式引流術(shù)后氣胸可治愈。
[Abstract]:Objective to explore the clinical characteristics of systemic lupus erythematosus (SLE) secondary pneumothorax, and to increase the understanding of it. Methods the pathogenesis, clinical manifestation, chest imaging characteristics and diagnosis and treatment of 1 cases of SLE patients with acute lupus pneumonia secondary pneumothorax were analyzed. "Systemic lupus erythematosus" and "PN". Eumothorax "retrieves the retrieval words in the PubMed database, using the" lupus "and" pneumothorax "as the retrieval word in the Wanfang database and the Chinese knowledge network database. The retrieval time is 1971~2016 years, and the related literature is reviewed. The results of the patients, women, 26 years old, for 3 months of fever, chest tightness, and 10 d in December 2016. Sore pneumonia. Treated with corticosteroids, cyclophosphamide and plasma exchange after admission. Patients who had sudden right chest pain during hospitalization, chest CT examination prompted right pneumothorax and closed thoracic drainage. 14 cases were reported, of which 2 cases were excluded because of data incompetence. The remaining 12 cases were 9 cases, male 3 cases (28 + 11.9). The clinical manifestations of the patients are sudden chest tightness and shortness of breath, often accompanied by the disappearance of the pneumothorax after closed thoracic drainage and a few patients undergoing thoracoscopic surgery. Conclusion SLE secondary pneumothorax is rare, which is often associated with SLE secondary pulmonary cavity, the rupture of the capsule cavity, and most patients after closed thoracic drainage of pneumothorax. Cure.
【作者單位】： 南京醫(yī)科大學(xué)第一附屬醫(yī)院呼吸與危重癥醫(yī)學(xué)科;皖南醫(yī)學(xué)院弋磯山醫(yī)院呼吸內(nèi)科;南京醫(yī)科大學(xué)第一附屬醫(yī)院風(fēng)濕免疫科;
【分類號】：R593.243

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