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不同b值磁共振彌散加權(quán)成像在鑒別前列腺癌和前列腺增生中的價(jià)值

發(fā)布時(shí)間:2018-06-02 09:01

  本文選題:前列腺癌 + 前列腺增生。 參考:《中國(guó)老年學(xué)雜志》2017年14期


【摘要】:目的探討不同b值3.0T磁共振彌散加權(quán)成像(DWI)在鑒別前列腺癌(PCa)和前列腺增生(BPH)的價(jià)值及合適的b值。方法經(jīng)穿刺活檢或手術(shù)病理確診的PCa患者40例,BPH患者31例,分別接受不同b值DWI掃描獲得感興趣區(qū)的表現(xiàn)擴(kuò)散系數(shù)(ADC)值,b值分別為300,800和1 000 s/mm~2,對(duì)比分析不同b值條件下PCa與BPH的ADC值差異,并采用受試者工作特征曲線(ROC)確定診斷PCa的靈敏度和特異度。結(jié)果不同b值條件下,PCa患者ADC值分別為(1.06±0.06)×10~(-3)mm~2/s,(0.83±0.04)×10~(-3)mm~2/s,(0.73±0.03)×10~(-3)mm~2/s,BPH患者ADC值分別為(1.38±0.06)×10~(-3)mm~2/s,(1.24±0.06)×10~(-3)mm~2/s,(1.18±0.04)×10~(-3)mm~2/s,同一b值條件下,兩組結(jié)果差異有統(tǒng)計(jì)學(xué)意義(P0.05)。DWI b 300,DWI b 800,DWI b 1 000診斷PCa的靈敏度和特異度分別為73.8%、76.3%,74.3%、75.0%,88.2%、84.0%。結(jié)論 ADC值對(duì)鑒別診斷PCa和BPH可提供定性和定量信息,當(dāng)b=1 000 s/mm~2時(shí),DWI對(duì)診斷PCa有較高的靈敏度和特異度。
[Abstract]:Objective to investigate the value and appropriate b value of 3.0T DWI in differentiating prostate cancer (PCA) from benign prostatic hyperplasia (BPH). Methods there were 31 patients with PCa diagnosed by biopsy or operation. The apparent diffusion coefficient (DWI) of the region of interest was 300800 and 1 000 s / m / m ~ (-2), respectively. The difference of ADC value between PCa and BPH was compared and analyzed under different b values. The sensitivity and specificity of diagnosis of PCa were determined by the operating characteristic curve of subjects. 緇撴灉涓嶅悓b鍊兼潯浠朵笅,PCa鎮(zhèn)h,

本文編號(hào):1968198

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