Polylactide（PLA） microspheres were prepared using the solid-in-oil（S/O） spray-drying method to achieve the sustained release of a hydrophilic drug for the treatment of tuberculosis, via intratracheal instillation. Isoniazid（IN）, a low-molecular-weight hydrophilic drug, was used as a model drug. The effects of various sizes of micronized IN powder, different drug/polymer ratios, spray-drying process parameters, and drug-release characteristics were studied to optimize the manufacturing parameters... 

【文章來(lái)源】：Science China（Life Sciences）. 2016,59(07)SCICSCD

【文章頁(yè)數(shù)】：8 頁(yè)

【部分圖文】：

圖.曰口』目石m倉(cāng)(h1

圖.曰口』目石m倉(cāng)(h1


本文編號(hào)：3489125