慢性乙型肝炎藥物治療研究進展
發(fā)布時間:2021-08-14 14:52
慢性乙型病毒性肝炎(CHB)作為一種危害性大、傳染性強的疾病,一直以來都是世界性醫(yī)療難題。隨著抗病毒藥物的不斷研究,人們對于CHB的治愈方式也有了新的認識。該文系統(tǒng)介紹了靶向乙型肝炎病毒(HBV)生命周期的藥物及免疫治療方法,可為全面了解疾病的演進與進展提供參考,以逐步實現(xiàn)從多個方面、多個機制入手徹底治愈CHB。
【文章來源】:現(xiàn)代醫(yī)藥衛(wèi)生. 2020,36(14)
【文章頁數(shù)】:4 頁
【文章目錄】:
1 靶向HBV的藥物
1.1 進入抑制劑
1.2 靶向cccDNA
1.3 靶向病毒的轉(zhuǎn)錄
1.4 靶向病毒核衣殼
1.6 靶向DNA聚合酶
2 免疫治療
2.1 模式識別受體(PRR)相關(guān)性受體激動劑
2.2 抗病毒疫苗
2.3 T細胞相關(guān)性免疫
2.4 靶向免疫檢查點
2.5 干擾素類
3 展望
【參考文獻】:
期刊論文
[1]Hepatitis B virus therapy:What’s the future holding for us?[J]. Sobia Manzoor,Muhammad Saalim,Muhammad Imran,Saleha Resham,Javed Ashraf. World Journal of Gastroenterology. 2015(44)
[2]Therapeutic effect of autologous dendritic cell vaccine on patients with chronic hepatitis B: A clinical study[J]. Min Chen, Hong Ren, the Research Institute for Viral Hepatitis, Chongqing University of Medical Sciences, Chongqing 400010, China Yong-Guo Li, Da-Zhi Zhang, Zhi-Yi Wang, Wei-Qun Zeng, Xiao-Feng Shi, Yuan Guo, Shu-Hua Guo, Hong Ren, Liver Disease Center of Chongqing City, the Second Affiliated Hospital of Chongqing University of Medical Sciences, Chongqing 400010, China. World Journal of Gastroenterology. 2005(12)
本文編號:3342668
【文章來源】:現(xiàn)代醫(yī)藥衛(wèi)生. 2020,36(14)
【文章頁數(shù)】:4 頁
【文章目錄】:
1 靶向HBV的藥物
1.1 進入抑制劑
1.2 靶向cccDNA
1.3 靶向病毒的轉(zhuǎn)錄
1.4 靶向病毒核衣殼
1.6 靶向DNA聚合酶
2 免疫治療
2.1 模式識別受體(PRR)相關(guān)性受體激動劑
2.2 抗病毒疫苗
2.3 T細胞相關(guān)性免疫
2.4 靶向免疫檢查點
2.5 干擾素類
3 展望
【參考文獻】:
期刊論文
[1]Hepatitis B virus therapy:What’s the future holding for us?[J]. Sobia Manzoor,Muhammad Saalim,Muhammad Imran,Saleha Resham,Javed Ashraf. World Journal of Gastroenterology. 2015(44)
[2]Therapeutic effect of autologous dendritic cell vaccine on patients with chronic hepatitis B: A clinical study[J]. Min Chen, Hong Ren, the Research Institute for Viral Hepatitis, Chongqing University of Medical Sciences, Chongqing 400010, China Yong-Guo Li, Da-Zhi Zhang, Zhi-Yi Wang, Wei-Qun Zeng, Xiao-Feng Shi, Yuan Guo, Shu-Hua Guo, Hong Ren, Liver Disease Center of Chongqing City, the Second Affiliated Hospital of Chongqing University of Medical Sciences, Chongqing 400010, China. World Journal of Gastroenterology. 2005(12)
本文編號:3342668
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