四川省鉤端螺旋體病高發(fā)縣報告病例的準確性調(diào)查研究
發(fā)布時間:2018-11-28 12:45
【摘要】:目的了解四川省鉤端螺旋體病高發(fā)地區(qū)報告鉤體病例準確性,為進一步控制鉤體病流行提供科學依據(jù)。方法采集2012年鉤體病高發(fā)地區(qū)報告臨床診斷病例血清進行鉤體菌培養(yǎng),血清學診斷,對鉤體病檢測結(jié)果為陰性的標本進行乙腦、出血熱和立克次體檢測。結(jié)果共采集87例報告病例的血清標本,培養(yǎng)出4株鉤體菌,鉤體菌培養(yǎng)陽性率為4.6%。采集64份病例急性期和恢復期雙份血清進行鉤體病檢測,其中54例陽性,陽性率為84.4%,采集23份病例單份血清,其中6份鉤體菌檢測陽性,陽性率為26.1%。對27份鉤體檢測陰性標本進行乙腦ELISA檢測,陽性1例,出血熱、立克次體檢測結(jié)果均為陰性。結(jié)論四川省鉤體病高發(fā)地區(qū)臨床診斷鉤體病準確性較高,但依然需要加強病例雙份血清采集和檢測。
[Abstract]:Objective to investigate the accuracy of reporting leptospirosis cases in high incidence areas of Leptospira in Sichuan Province, and to provide scientific basis for further control of leptospirosis. Methods the serological diagnosis of leptospirosis in the high incidence area of leptospirosis in 2012 was carried out by serological diagnosis. The samples with negative results of leptospirosis were tested for je, hemorrhagic fever and Rickettsia. Results A total of 87 serum samples of reported cases were collected and 4 strains of Leptospira were cultured. The positive rate of Leptospira culture was 4.6%. In 64 cases of acute and convalescent stage, 54 cases were positive for leptospirosis, the positive rate was 84.4, and 23 cases were single serums, 6 of them were positive for Leptospira, the positive rate was 26.1%. In 27 samples with negative Leptospira test, the results of ELISA were positive in 1 case, hemorrhagic fever and Rickettsia were all negative. Conclusion the accuracy of clinical diagnosis of leptospirosis in Sichuan Province is high, but it is still necessary to strengthen the collection and detection of double serum samples.
【作者單位】: 四川省疾病預防控制中心;中國疾病預防控制中心;
【分類號】:R514.4
[Abstract]:Objective to investigate the accuracy of reporting leptospirosis cases in high incidence areas of Leptospira in Sichuan Province, and to provide scientific basis for further control of leptospirosis. Methods the serological diagnosis of leptospirosis in the high incidence area of leptospirosis in 2012 was carried out by serological diagnosis. The samples with negative results of leptospirosis were tested for je, hemorrhagic fever and Rickettsia. Results A total of 87 serum samples of reported cases were collected and 4 strains of Leptospira were cultured. The positive rate of Leptospira culture was 4.6%. In 64 cases of acute and convalescent stage, 54 cases were positive for leptospirosis, the positive rate was 84.4, and 23 cases were single serums, 6 of them were positive for Leptospira, the positive rate was 26.1%. In 27 samples with negative Leptospira test, the results of ELISA were positive in 1 case, hemorrhagic fever and Rickettsia were all negative. Conclusion the accuracy of clinical diagnosis of leptospirosis in Sichuan Province is high, but it is still necessary to strengthen the collection and detection of double serum samples.
【作者單位】: 四川省疾病預防控制中心;中國疾病預防控制中心;
【分類號】:R514.4
【共引文獻】
相關期刊論文 前10條
1 張士堯;浦昀;徐坤;李金華;原野;鞠文;李娟;;重組鉤端螺旋體多抗原位點同源合成基因的表達及其抗原性鑒定[J];吉林大學學報(醫(yī)學版);2012年03期
2 齊海霞;張海云;鄧小雨;楊秀環(huán);白如念;蔣秀高;聶一新;李秀文;;犬、貓鉤端螺旋體病的流行病學調(diào)查[J];中國畜牧獸醫(yī);2012年11期
3 徐國英;潘敏楠;肖方震;周淑Y,
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