【摘要】：目的了解賀州市孕產(chǎn)期艾滋病抗體檢測(cè)、感染孕產(chǎn)婦及感染孕產(chǎn)婦母子抗艾滋病病毒藥物應(yīng)用與檢測(cè)狀況及變化趨勢(shì)。方法利用國(guó)家預(yù)防艾滋病母嬰傳播管理信息網(wǎng)絡(luò)直報(bào)系統(tǒng),收集和整理賀州市2006—2012年孕產(chǎn)期艾滋病抗體、CD+4T淋巴細(xì)胞、病毒載量等檢測(cè)信息、HIV感染孕產(chǎn)婦孕期、產(chǎn)時(shí)以及所生兒童應(yīng)用抗逆轉(zhuǎn)錄病毒藥物等相關(guān)信息。對(duì)相關(guān)數(shù)據(jù)進(jìn)行描述性分析和年度趨勢(shì)變化分析。結(jié)果 2006—2012年賀州市共有130 743例孕產(chǎn)婦接受艾滋病抗體檢測(cè),其中孕產(chǎn)婦HIV抗體檢測(cè)率從2006年的88.68%上升至2012年的99.96%。7年中,賀州市共發(fā)現(xiàn)230例HIV感染孕產(chǎn)婦。2006—2012年分別有67.86%、70.59%、82.05%、82.14%、97.30%、100%和100%的感染孕產(chǎn)婦應(yīng)用了抗病毒藥物,并呈逐年上升趨勢(shì)(χ2=6.30,P0.05),感染產(chǎn)婦孕28周前(含28周)開(kāi)始應(yīng)用三聯(lián)方案比例也呈逐年上升趨勢(shì);感染產(chǎn)婦所生嬰兒抗逆轉(zhuǎn)錄病毒藥物應(yīng)用比例自2010年均達(dá)到100%。結(jié)論孕期抗體檢測(cè)比例仍有待進(jìn)一步提高。盡管感染孕產(chǎn)婦及所生嬰兒抗病毒藥物應(yīng)用比例逐年上升,但感染產(chǎn)婦在孕早期抗病毒藥物應(yīng)用比例比較低,需要進(jìn)一步提高孕早期抗體檢測(cè)比例及感染產(chǎn)婦在孕早期抗病毒藥物應(yīng)用比例,從而減少母嬰傳播的風(fēng)險(xiǎn)。
[Abstract]:Objective to investigate the status and trend of anti-HIV drugs used and detected in pregnant and pregnant women and infected pregnant women in Hezhou City. Methods the information of CD 4T lymphocytes, CD 4T lymphocytes and viral load of pregnant women in Hezhou City during pregnancy and delivery period from 2006 to 2012 were collected and sorted by the National Network Direct reporting system for the Prevention of Mother-to-Child Transmission of AIDS. The pregnant women were infected with HIV during pregnancy. Information related to the use of antiretroviral drugs at birth and in children born. Carry on descriptive analysis and annual trend change analysis to relevant data. Results A total of 130,743 pregnant women were tested for HIV antibody in Hezhou City from 2006 to 2012. The HIV antibody detection rate of pregnant women increased from 88.68% in 2006 to 99.96.7 years in 2012. A total of 230 pregnant and lying-in women with HIV infection were found in Hezhou City. From 2006 to 2012, 67.86% of the pregnant and lying-in women with HIV were 70.59 and 82.05%, and 82.14%, 97.30% and 100% of the infected pregnant and lying-in women received antiviral drugs, respectively, from 2006 to 2012. The proportion of pregnant women who began to use triple regimen before 28 weeks of pregnancy (including 28 weeks) showed an increasing trend year by year. The proportion of antiretrovirals used in infants born to infected women has reached 100 since 2010. Conclusion the ratio of antibody detection in pregnancy needs to be further improved. Although the proportion of antiviral drugs used in infected pregnant women and their babies has increased year by year, the proportion of infected women using antiviral drugs in early pregnancy is relatively low. In order to reduce the risk of mother-to-child transmission, it is necessary to further increase the detection rate of antibodies in early pregnancy and the proportion of antiviral drugs used in infected women in early pregnancy.
【作者單位】： 賀州市婦幼保健院;中國(guó)疾病預(yù)防控制中心婦幼保健中心;
【分類(lèi)號(hào)】：R193;R512.91

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