不同類型冠心病患者心律失常的相關(guān)因素
發(fā)布時(shí)間：2018-10-22 10:54
【摘要】：目的探討不同類型冠心病患者心律失常發(fā)生情況的臨床相關(guān)因素。方法 1 014例冠心病患者,分為急性冠脈綜合征(ACS)和慢性缺血綜合征(CIS)兩種類型,采用動(dòng)態(tài)心電圖檢查記錄所發(fā)生的心律失常類型,分析比較各組中房性心律失常或室性心律失常的發(fā)生與年齡、性別、高血壓病、糖尿病、高脂血癥、冠脈病變支數(shù)、血鉀、腦尿鈉肽(BNP)、左室射血分?jǐn)?shù)(LVEF)和左室舒張末期內(nèi)徑(LVEDD)值的相關(guān)性,并通過logistic回歸分析,找出心律失常發(fā)生情況的相關(guān)因素。結(jié)果 (1)ACS患者的年齡、性別、高血壓、糖尿病、高脂血癥、冠脈病變支數(shù)、BNP、LVEF及LVEDD值在發(fā)生房性或室性心律失常中的差異無統(tǒng)計(jì)學(xué)意義,而血鉀值在發(fā)生房性或室性心律失常中的差異有統(tǒng)計(jì)學(xué)意義(P0.05);logistic回歸分析顯示,ACS患者發(fā)生室性心律失常的獨(dú)立相關(guān)因素是低血鉀(P=0.027,OR:2.009,95%CI:1.084-3.726)。(2)CIS患者的年齡、性別、高血壓病、糖尿病、高脂血癥、冠脈病變支數(shù)、血鉀值在發(fā)生房性或室性心律失常中的差異無統(tǒng)計(jì)學(xué)意義,而BNP、LVEF及LVEDD值在發(fā)生房性或室性心律失常中的差異有統(tǒng)計(jì)學(xué)意義(P0.05);logistic回歸分析顯示,CIS患者發(fā)生室性心律失常的獨(dú)立相關(guān)因素是LVEF降低(P=0.048,OR:3.561,95%CI:1.010-12.553)。結(jié)論低血鉀可能是ACS組患者發(fā)生室性心律失常的獨(dú)立相關(guān)因素;而LVEF降低可能是CIS組患者發(fā)生室性心律失常的獨(dú)立相關(guān)因素。
[Abstract]:Objective to investigate the clinical related factors of arrhythmia in patients with different types of coronary heart disease. Methods 1,014 patients with coronary heart disease were divided into two types: acute coronary syndrome (ACS) and chronic ischemic syndrome (CIS). To compare the incidence of atrial arrhythmia and ventricular arrhythmia with age, sex, hypertension, diabetes mellitus, hyperlipidemia, coronary artery disease, blood potassium, and compare the incidence of atrial arrhythmia and ventricular arrhythmia in each group. The correlation between left ventricular ejection fraction (LVEF) and left ventricular end-diastolic diameter (LVEDD) of brain natriuretic peptide (BNP),) was analyzed by logistic regression analysis. Results (1) there was no significant difference in age, sex, hypertension, diabetes, hyperlipidemia, coronary artery disease branches, BNP,LVEF and LVEDD values in patients with atrial or ventricular arrhythmias. However, there was significant difference in serum potassium levels in patients with atrial or ventricular arrhythmias (P0.05); logistic regression analysis showed that the independent factors associated with ventricular arrhythmias in patients with ACS were the age, sex, hypertension, diabetes mellitus, age, sex, hypertension, diabetes mellitus) of patients with CIS with hypokalemia (P < 0.027): OR: 2.009 / 95CI: 1.084-3.726). (. There was no significant difference in hyperlipidemia, coronary artery disease branches and serum potassium levels in atrial or ventricular arrhythmias. The difference of BNP,LVEF and LVEDD in the occurrence of atrial or ventricular arrhythmias was statistically significant (P0.05); logistic regression analysis showed that the independent factor related to the occurrence of ventricular arrhythmias in CIS patients was the decrease of LVEF (P < 0.048): O: 3.56195 CI: 1.010-12.553). Conclusion hypokalemia may be an independent correlation factor for ventricular arrhythmias in ACS group, while the decrease of LVEF may be an independent correlation factor for ventricular arrhythmia in CIS group.
【作者單位】： 中國(guó)醫(yī)科大學(xué)附屬第一醫(yī)院心血管內(nèi)科;
【基金】：遼寧省社會(huì)發(fā)展攻關(guān)計(jì)劃項(xiàng)目資助(20122250019)
【分類號(hào)】：R514.4
本文編號(hào)：2286951
[Abstract]:Objective to investigate the clinical related factors of arrhythmia in patients with different types of coronary heart disease. Methods 1,014 patients with coronary heart disease were divided into two types: acute coronary syndrome (ACS) and chronic ischemic syndrome (CIS). To compare the incidence of atrial arrhythmia and ventricular arrhythmia with age, sex, hypertension, diabetes mellitus, hyperlipidemia, coronary artery disease, blood potassium, and compare the incidence of atrial arrhythmia and ventricular arrhythmia in each group. The correlation between left ventricular ejection fraction (LVEF) and left ventricular end-diastolic diameter (LVEDD) of brain natriuretic peptide (BNP),) was analyzed by logistic regression analysis. Results (1) there was no significant difference in age, sex, hypertension, diabetes, hyperlipidemia, coronary artery disease branches, BNP,LVEF and LVEDD values in patients with atrial or ventricular arrhythmias. However, there was significant difference in serum potassium levels in patients with atrial or ventricular arrhythmias (P0.05); logistic regression analysis showed that the independent factors associated with ventricular arrhythmias in patients with ACS were the age, sex, hypertension, diabetes mellitus, age, sex, hypertension, diabetes mellitus) of patients with CIS with hypokalemia (P < 0.027): OR: 2.009 / 95CI: 1.084-3.726). (. There was no significant difference in hyperlipidemia, coronary artery disease branches and serum potassium levels in atrial or ventricular arrhythmias. The difference of BNP,LVEF and LVEDD in the occurrence of atrial or ventricular arrhythmias was statistically significant (P0.05); logistic regression analysis showed that the independent factor related to the occurrence of ventricular arrhythmias in CIS patients was the decrease of LVEF (P < 0.048): O: 3.56195 CI: 1.010-12.553). Conclusion hypokalemia may be an independent correlation factor for ventricular arrhythmias in ACS group, while the decrease of LVEF may be an independent correlation factor for ventricular arrhythmia in CIS group.
【作者單位】： 中國(guó)醫(yī)科大學(xué)附屬第一醫(yī)院心血管內(nèi)科;
【基金】：遼寧省社會(huì)發(fā)展攻關(guān)計(jì)劃項(xiàng)目資助(20122250019)
【分類號(hào)】：R514.4
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