【摘要】：目的回顧性分析11例輸入性羅阿絲蟲病患者的臨床特征。方法收集首都醫(yī)科大學附屬北京友誼醫(yī)院2012年1月-2016年7月確診的11例輸入性羅阿絲蟲病患者臨床和實驗室數(shù)據(jù)并進行分析。結(jié)果 11例羅阿絲蟲病患者均有羅阿絲蟲疫區(qū)工作生活史�；颊呔杏巫咝云は履[塊,94.0%伴有瘙癢,1例患者檢出眼結(jié)膜成蟲。45.45%的患者進行了T淋巴細胞亞群和免疫球蛋白抗體檢測,其中IgE抗體水平增高,絲蟲抗原陽性。1例患者絲蟲IgG4抗體陽性。血查微絲蚴均陰性。所有患者口服均阿苯達唑治療,治療1個療程9例,2個療程治療2例,3例出現(xiàn)不良反應(yīng),所有患者至今隨訪無復(fù)發(fā)。結(jié)論綜合流行病學史分析,有游走性皮下腫塊,血嗜酸性粒細胞增多,絲蟲抗原和抗體陽性可診斷為羅阿絲蟲病。阿苯達唑單一用藥治療羅阿絲蟲病效果良好。
[Abstract]:Objective to retrospectively analyze the clinical features of 11 patients with imported Roa filariasis. Methods the clinical and laboratory data of 11 imported Roa filariasis patients from January 2012 to July 2016 in Beijing Friendship Hospital affiliated to Capital Medical University were collected and analyzed. Results all 11 patients with Roa filariasis had a working life history in the infected area of Roa filariasis. 94. 0% of the patients had walking subcutaneous masses accompanied with pruritus. 45.45% of the patients detected conjunctival adult worms were examined for T lymphocyte subsets and immunoglobulin antibodies, in which the level of IgE antibody was increased. IgG4 antibody was positive in 1. 1 patients with positive filarial antigen. Microfilariae were negative in blood. All the patients were treated by oral mebendazole, 9 patients were treated with one course of treatment, and 3 patients with adverse reactions were treated with 2 courses of treatment. Conclusion according to the analysis of epidemiologic history, there are wandering subcutaneous masses, eosinophils in blood, and positive antigens and antibodies of filariasis can be diagnosed as Roa filariasis. Albendazole alone is effective in the treatment of Roa filariasis.
【作者單位】： 首都醫(yī)科大學附屬北京友誼醫(yī)院北京熱帶醫(yī)學研究所熱帶病防治研究北京市重點實驗室;
【基金】：北京市醫(yī)院管理局臨床技術(shù)創(chuàng)新項目(No.XMLX201502) 北京市衛(wèi)生系統(tǒng)高層次衛(wèi)生技術(shù)人才培養(yǎng)計劃(No.2015-3-010) 國家臨床重點�？平ㄔO(shè)項目
【分類號】：R532.15

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