【摘要】：目的分析亞臨床型生殖器皰疹(GH)患者的病毒脫排特點(diǎn),為臨床治療提供依據(jù)。方法選取2014年6月—2016年6月間我院收治的亞臨床型GH患者142例,熒光定量PCR法檢測患者單純皰疹病毒(HSV)-DNA脫排情況,酶聯(lián)免疫吸附試驗(yàn)(ELISA)檢測患者血清Ig G抗體類型。分析年齡、性別、抗體類型及病程長短、發(fā)病頻率對(duì)病毒脫排陽性率的影響。結(jié)果 142例患者中HSV-DNA陽性率為49.3%,女性的病毒脫排陽性率高于男性(P0.05)。血清HSV-ⅠIg G++HSV-ⅡIg G+與單純HSV-ⅡIg G+患者病毒脫排陽性率差異無統(tǒng)計(jì)學(xué)意義,但二者均高于單純HSV-ⅠIg G+患者。病程≤6年的患者病毒脫排陽性率高于6年者,頻發(fā)患者(復(fù)發(fā)≥6次/年)高于少發(fā)患者(復(fù)發(fā)6次/年,均P0.05)。病程≤6年的患者中,頻發(fā)患者高于少發(fā)患者,而病程6年的患者中,頻發(fā)與少發(fā)患者病毒脫排陽性率差異無統(tǒng)計(jì)學(xué)意義(P0.05)。同時(shí)女性患者HSV-Ⅱ感染率高于男性(P0.05)。結(jié)論亞臨床型GH患者的病毒脫排陽性率與性別、血清抗體類型、病程及發(fā)病頻率等因素密切相關(guān)。
[Abstract]:Objective to analyze the characteristics of virus stripping in patients with subclinical genital herpes (GH) and to provide evidence for clinical treatment. Methods 142 patients with subclinical GH were selected from June 2014 to June 2016 in our hospital. The (HSV)-DNA desorption of herpes simplex virus (HSV) was detected by fluorescence quantitative PCR assay and the serum IgG antibody type was detected by Elisa (ELISA). The effect of age, sex, antibody type, duration of disease and frequency of disease on the positive rate of virus demagination was analyzed. Results the positive rate of HSV-DNA was 49.3% in 142 patients, and the positive rate of virus demagination in women was higher than that in men (P0.05). There was no significant difference between HSV- 鈪，

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