本文選題：艾滋病 + 卡氏肺孢子蟲(chóng)肺炎�。� 參考：《中國(guó)現(xiàn)代醫(yī)生》2016年10期

【摘要】：目的探討艾滋病(AIDS)合并卡氏肺孢子菌肺炎(PCP)的臨床表現(xiàn)、診斷和治療。方法采用回顧性分析的方法收集寧夏醫(yī)科大學(xué)總醫(yī)院感染疾病科自2014年10月~2015年1月間收治的艾滋病合并卡氏肺孢子菌肺炎患者的臨床特點(diǎn)、實(shí)驗(yàn)室檢查和64排螺旋CT表現(xiàn)。結(jié)果咳嗽、持續(xù)低熱、進(jìn)行性呼吸困難、紫紺是PCP最常見(jiàn)的臨床癥狀,CD~(4+)T淋巴細(xì)胞數(shù)為(1~400)個(gè)/μL;典型影像學(xué)表現(xiàn)為雙肺彌漫性磨玻璃樣滲出影;PCP患者均采用復(fù)方磺胺甲基異惡唑(SMZco)治療,如動(dòng)脈血氧分壓70 mmHg聯(lián)合強(qiáng)的松治療,如合并其他機(jī)會(huì)性感染予以相應(yīng)的治療;其中3例患者好轉(zhuǎn),1例患者死亡,1例患者放棄治療自動(dòng)出院。大多數(shù)患者因合并其他病原菌感染而死亡,且其CD~(4+)T淋巴細(xì)胞計(jì)數(shù)明顯低于病情好轉(zhuǎn)的患者。結(jié)論 PCP主要發(fā)生在AIDS晚期,如AIDS患者有低熱、呼吸困難、低氧血癥、體重下降等臨床表現(xiàn),且胸部CT表現(xiàn)為間質(zhì)紋理增粗、模糊或呈磨玻璃狀陰影,需留心AIDS合并PCP的可能,應(yīng)早期給予SMZco治療,嚴(yán)重患者可聯(lián)合糖皮質(zhì)激素沖擊治療。
[Abstract]:Objective to investigate the clinical manifestation, diagnosis and treatment of AIDS with Pneumocystis carinii pneumonia. Methods the clinical features, laboratory examination and 64-slice spiral CT findings of AIDS patients with pneumocystis carinii pneumonia admitted from October 2014 to January 2015 were collected by retrospective analysis. Results cough, persistent low fever, progressive dyspnea, Cyanosis is the most common clinical symptom of PCP. For example, the arterial partial pressure of oxygen 70 mmHg combined with prednisone, if combined with other opportunistic infections, should be treated accordingly, of which 3 patients had improved and 1 patient had died, and 1 patient had given up treatment and been discharged automatically. Most of the patients died from other pathogens, and the T lymphocyte count was significantly lower than that in the patients with improved condition. Conclusion PCP mainly occurs in the late stage of AIDS, such as low fever, dyspnea, hypoxemia, weight loss and so on. SMZco should be given early treatment, severe patients can be combined with glucocorticoid shock therapy.
【作者單位】： 寧夏醫(yī)科大學(xué);寧夏醫(yī)科大學(xué)總醫(yī)院感染疾病科;
【分類號(hào)】：R512.91;R563.1

【相似文獻(xiàn)】

相關(guān)期刊論文 前1條

1 李廷榮;李桓;王靜;王治倫;吳迪;劉原杰;;13例艾滋病患者HAART后HIV-RNA變化與CD4變化的關(guān)系分析[J];重慶醫(yī)學(xué);2006年10期

，

本文編號(hào)：2044159