本文選題：男男性接觸者 + 肛腸　； 參考：《中國(guó)感染控制雜志》2017年12期

【摘要】：目的了解男男性接觸者(MSM)肛腸尖銳濕疣患者中合并肛腸淋球菌、沙眼衣原體感染現(xiàn)況,為肛腸尖銳濕疣患者的臨床診療提供循證醫(yī)學(xué)依據(jù)。方法分別采取MSM人群中已確診肛腸尖銳濕疣患者(試驗(yàn)組)及非尖銳濕疣患者(對(duì)照組)的肛腸拭子,采用熒光定量PCR方法進(jìn)行淋球菌及沙眼衣原體的核酸片段檢測(cè)。同時(shí)采集調(diào)查對(duì)象的社會(huì)人口學(xué)及相關(guān)性行為學(xué)資料,進(jìn)行比較分析。結(jié)果共納入研究對(duì)象158例患者,其中試驗(yàn)組63例,對(duì)照組95例。試驗(yàn)組63例患者中淋球菌感染率為17.46%,沙眼衣原體感染率為28.57%,同時(shí)合并淋球菌及沙眼衣原體感染率為12.70%;對(duì)照組中淋球菌感染率為6.32%,沙眼衣原體感染率為9.47%,同時(shí)合并淋球菌及沙眼衣原體感染率為2.16%。試驗(yàn)組患者肛腸中的淋球菌、沙眼衣原體感染率及兩組疾病的合并感染率均高于對(duì)照組(均P0.05)。結(jié)論 MSM中肛腸尖銳濕疣患者中具有較高的淋球菌及沙眼衣原體的感染率。提示醫(yī)務(wù)人員臨床工作中應(yīng)重視肛腸尖銳濕疣患者肛腸部位的淋球菌、沙眼衣原體及其他性傳播感染的篩查。
[Abstract]:Objective to understand the current status of Chlamydia trachomatis infection in the anorectal condyloma acuminate condyloma (MSM) patients with anorectal condyloma, and to provide evidence-based medical basis for the clinical diagnosis and treatment of anorectal condyloma acuminate patients. Methods the anorectal condyloma acuminata patients (test group) and non acuminate condyloma acuminate patients (control group) of the anorectal (control group) were used respectively. The swab was used to detect the nucleic acid fragment of gonococci and Chlamydia trachomatis by fluorescence quantitative PCR. At the same time, the social demography and related behavioral data of the subjects were collected and compared. The results were included in 158 patients, including 63 in the experimental group and 95 in the control group. The rate of Neisseria gonorrhoeae infection was 1 in the experimental group of 63 patients. 7.46%, the infection rate of Chlamydia trachomatis was 28.57%, and the infection rate of Neisseria gonorrhoeae and Chlamydia trachomatis was 12.70%. The rate of Neisseria gonorrhoeae infection in the control group was 6.32%, the infection rate of Chlamydia trachomatis was 9.47%. At the same time, the rate of gonococcus and Chlamydia trachomatis in the 2.16%. test group were the Neisseria gonorrhoeae, the infection rate of Chlamydia trachomatis in the trachoma and two groups. The combined infection rate of the disease was higher than that of the control group (all P0.05). Conclusion the infection rate of gonococci and Chlamydia trachomatis in the patients with anorectal condyloma acuminata was higher in MSM. It was suggested that the medical staff should pay attention to the screening of gonococci, Chlamydia trachomatis and other sexually transmitted infections in the anorectal area of the patients with anorectal condyloma.
【作者單位】： 南通大學(xué)附屬醫(yī)院;
【基金】：南通市科技社會(huì)事業(yè)科技創(chuàng)新與示范項(xiàng)目(HS2014031)
【分類號(hào)】：R752.53

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