本文選題：Majocchi肉芽腫 + 紅色毛癬菌�。� 參考：《中國(guó)真菌學(xué)雜志》2016年05期

【摘要】：目的首次報(bào)道伏立康唑成功治療1例紅色毛癬菌引起的頑固性面部Majocchi肉芽腫,分析患者的臨床表現(xiàn)、病理特點(diǎn)、真菌學(xué)檢查及分子生物學(xué)鑒定結(jié)果,并總結(jié)英文報(bào)道病例。方法患者男,50歲,因面部浸潤(rùn)性紅斑潰瘍5a就診,取患處皮損進(jìn)行組織病理學(xué)檢查、真菌學(xué)檢查、藥物敏感試驗(yàn)及PCR檢測(cè)。結(jié)果診斷:紅色毛癬菌致面部Majocchi肉芽腫。治療:伏立康唑靜脈治療2周改伏立康唑片劑口服,治療4個(gè)月后患者原有皮損基本消退,真菌學(xué)陰性,無不良反應(yīng)。結(jié)論 Majocchi肉芽腫臨床罕見,復(fù)雜難治,療程長(zhǎng),易反復(fù),嚴(yán)重影響患者生活質(zhì)量,我們首次應(yīng)用伏立康唑成功治療頑固性Majocchi肉芽腫,為臨床治療難治性Majocchi肉芽腫提供新的診療經(jīng)驗(yàn)。
[Abstract]:Objective to report for the first time the successful treatment of a case of refractory facial Majocchi granuloma caused by Trichophyton rubrum. Methods the patient, aged 50 years, was treated for 5 years because of facial infiltrating erythema ulcer. Histopathological examination, mycological examination, drug sensitivity test and PCR test were performed. Results: Majocchi granuloma of face was caused by Trichophyton rubrum. Treatment: Volconazole tablets were given orally for 2 weeks. After 4 months of treatment, the original skin lesions were basically disappeared, mycology was negative, and no adverse reactions were found. Conclusion Majocchi granuloma is rare in clinical practice, complex and difficult to be treated. The course of treatment is long and easy to repeat, which seriously affects the quality of life of the patients. We successfully treated refractory Majocchi granuloma with Volconazole for the first time. To provide new experience for clinical treatment of refractory Majocchi granuloma.
【作者單位】： 南京軍區(qū)南京總醫(yī)院皮膚科;中國(guó)醫(yī)學(xué)科學(xué)院皮膚病醫(yī)院;
【分類號(hào)】：R756.6
，

本文編號(hào)：1986272