青海省果洛藏族自治州棘球蚴病和棘球絳蟲病流行情況調(diào)查
發(fā)布時(shí)間:2018-06-01 02:10
本文選題:青海 + 果洛; 參考:《中國寄生蟲學(xué)與寄生蟲病雜志》2017年04期
【摘要】:目的了解青海省果洛藏族自治州(簡稱果洛州)人與動(dòng)物棘球蚴病的流行情況。方法 2012年6-8月,在果洛州班瑪、達(dá)日、甘德、久治、瑪多、瑪沁等6個(gè)縣各抽取2~3個(gè)鄉(xiāng)(鎮(zhèn)),對(duì)1歲以上常住居民進(jìn)行B超檢查,計(jì)算人群棘球蚴病檢出率;使用Ig G抗體檢測試劑盒ELISA檢測血清抗棘球蚴抗體,計(jì)算人群血清抗體陽性率。采用內(nèi)臟剖檢法調(diào)查嚙齒動(dòng)物鼠類及牲畜棘球蚴感染情況,現(xiàn)場隨機(jī)采集家犬糞,ELISA檢測糞抗原陽性情況。結(jié)果 B超檢查共15 890人,查出患病者826例,檢出率為5.20%(826/15 890)。ELISA檢測共1 200人,血清抗體陽性率為16.75%(201/1 200)。達(dá)日縣人群棘球蚴病檢出率最高,為11.93%(430/3 605);甘德縣血清抗體陽性率最高,為48.15%(65/135),其次為班瑪縣(12.77%,136/1 065)。女性棘球蚴病檢出率和血清抗體陽性率分別為6.37%(499/7 839)和26.01%(142/546),均高于男性的4.06%(327/8 051)和9.02%(59/654)(P0.01)。牧民、宗教人士、學(xué)生和家務(wù)人員的棘球蚴病檢出率均較高,分別為5.24%(700/13 370)、6.46%(41/635)、8.39%(25/298)和5.68%(18/317)。60~、30~和≥70年齡組棘球蚴病檢出率均較高,分別為6.91%(76/1 100)、6.25%(255/4 078)和8.08%(37/458);≥70、60~、40~年齡組血清抗體陽性率均較高,分別為48.28%(14/29)、28.57%(20/70)、23.12%(40/173)。文盲人群的棘球蚴病檢出率和血清抗體陽性率均最高,為5.85%(431/7 365)和62.61%(72/115)。冬季定居夏季游牧人群的棘球蚴病檢出率和血清抗體陽性率最高,為6.36%(642/10 087)和60.49%(147/243)。不同地區(qū)、性別、職業(yè)、年齡組、文化程度以及不同居住方式間差異有統(tǒng)計(jì)學(xué)意義(P0.05)。果洛州鼠類棘球蚴感染率為2.41%(98/4 058),其中久治縣最高,為4.82%(49/1 016);終宿主犬糞抗原陽性率為14.90%(303/2 034),其中瑪沁縣最高,為18.76%(160/753);中間宿主牛棘球蚴感染率為28.37%(570/2 009),其中達(dá)日縣最高,為62.80%(314/500)。不同地區(qū)間中間宿主牛、嚙齒動(dòng)物鼠類的感染率和終末宿主犬糞抗原陽性率的差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論果洛州棘球蚴病疫情流行嚴(yán)重,犬是主要傳染源。
[Abstract]:Objective to investigate the prevalence of human and animal echinococcosis in Guoluo Tibetan Autonomous Prefecture of Qinghai Province. Methods from June to August, 2012, 2 ~ 3 townships were selected from 6 counties in Guoruo County, including Banma, Dagri, Gander, Jiuzhi, Maduo and Maqin. B ultrasonic examination was performed on residents aged 1 and above, and the detectable rate of echinococcosis was calculated. Elisa was used to detect the serum anti-echinococcal antibody and the positive rate of serum antibody was calculated. The infection of rat and livestock echinococcosis in rodents and livestock was investigated by visceral dissecting method. The fecal antigen was detected by Elisa at random. Results A total of 15 890 patients were detected by B ultrasound, 826 cases were diagnosed, the detection rate was 5. 20% and 1 200 cases were detected by Elisa. The positive rate of serum antibody was 16. 75% / 201 / 1 200. The detection rate of echinococcosis was the highest in Dati County, 11.933%, 430%, 3605%, and the highest in Gande County, which was 48.15%, 65%, 135%, followed by Banma County, 12.77% 136R / 1065%. The detectable rate of echinococcosis and the positive rate of serum antibody in women were 6.3799 / 7 839) and 26.01% / 142 / 546 respectively, which were higher than those in men's 4.06% (3.27% 8 051) and 9.02% (59% 654% P 0.01). The detection rates of echinococcosis in herdsmen, religious personages, students and domestic workers were higher, at 5.24, respectively, which were 700 / 13 370 / 6.46 and 41 / 635 / 8.39 / 298) and 5.68% respectively, and the positive rates of echinococcosis were higher in the age group of 18 / 18 / 317.60 ~ and 鈮,
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