本文選題：慢性乙型肝炎 + 肝纖維化　； 參考：《河南中醫(yī)》2016年01期

【摘要】：目的:觀察血府逐瘀湯聯(lián)合恩替卡韋治療慢性乙型肝炎肝纖維化的臨床療效。方法:將60例慢性乙型肝炎肝纖維化患者隨機(jī)分為對(duì)照組和觀察組,每組各30例。對(duì)照組應(yīng)用恩替卡韋治療,觀察組在對(duì)照組的基礎(chǔ)上聯(lián)合血府逐瘀湯。觀察兩組患者的臨床療效及治療前后肝纖維化指標(biāo)的變化情況。結(jié)果:觀察組有效率為90.00%,對(duì)照組有效率為63.33%,兩組有效率比較,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。兩組患者治療前肝纖維化指標(biāo)差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。治療后兩組患者血清透明質(zhì)酸(hyaluronic acid,HA)、層粘蛋白(laminin,LN)、Ⅲ型前膠原PCⅢ、Ⅳ型膠原Ⅳ-C各項(xiàng)指標(biāo)均較治療前顯著降低,且觀察組優(yōu)于對(duì)照組,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:血府逐瘀湯聯(lián)合恩替卡韋治療慢性乙型肝炎肝纖維化臨床療效顯著,且能改善患者肝纖維化水平。
[Abstract]:Objective: to observe the clinical effect of Xuefu Zhuyu decoction combined with entecavir on chronic hepatitis B liver fibrosis. Methods: 60 patients with chronic hepatitis B liver fibrosis were randomly divided into control group and observation group with 30 cases in each group. The control group was treated with entecavir, and the observation group combined with Xuefu Zhuyu decoction on the basis of the control group. To observe the clinical effect of the two groups and the changes of hepatic fibrosis indexes before and after treatment. Results: the effective rate was 90.00g in the observation group and 63.33 in the control group. The difference between the two groups was statistically significant (P 0.05). There was no significant difference in hepatic fibrosis between the two groups before treatment (P 0.05). After treatment, the serum hyaluronic acidonium, laminin (LNN), procollagen 鈪，

本文編號(hào)：1931303