本文選題：感染性腹瀉 + 病毒��； 參考：《現(xiàn)代預防醫(yī)學》2017年13期

【摘要】：目的了解徐州市感染性腹瀉的病毒病原學特點和流行特征,為制定科學的防治策略提供理論依據(jù)。方法運用Real-Time PCR方法對2013-2015年徐州市腹瀉病監(jiān)測哨點醫(yī)院采集的糞便標本進行病毒核酸檢測;采用描述性流行病學分析方法對病原學監(jiān)測結果進行分析。結果 2013-2015年共檢測感染性腹瀉標本1 351份,病毒陽性標本數(shù)為216份,陽性率為15.99%,其中輪狀病毒檢出率最高,其次為諾如病毒和星狀病毒。2013-2015年腹瀉病毒陽性檢出率分別為28.08%、10.45%、9.91%,呈現(xiàn)逐年遞減的趨勢。2013-2015年,輪狀病毒和星狀病毒的檢出率呈逐年下降趨勢,諾如病毒的檢出率呈逐年上升趨勢。腹瀉病毒檢出高峰為5~7月和9~12月。5歲以下嬰幼兒較其他年齡組更易感染。結論 2013-2015年徐州市感染性腹瀉的主要致病病毒為輪狀病毒、諾如病毒和星狀病毒,各年的病毒病原學構成有所不同;具有明顯的季節(jié)流行和人群分布特點,應加強病原學監(jiān)測和疾病監(jiān)測預警,針對重點人群和流行毒株適時采取有效防控措施。
[Abstract]:Objective to understand the pathogenic characteristics and epidemic characteristics of infectious diarrhea in Xuzhou, and to provide theoretical basis for making scientific prevention and treatment strategies. Methods Real-Time PCR method was used to detect viral nucleic acid in stool samples collected from surveillance sentinel hospitals of Xuzhou from 2013 to 2015, and descriptive epidemiological analysis was used to analyze the results of etiological surveillance. Results A total of 1 351 infectious diarrhea specimens were detected in 2013-2015, 216 of which were positive for the virus, the positive rate was 15.99. The detection rate of rotavirus was the highest. Secondly, the positive rates of norovirus and stellate virus in 2013-2015 were 28.08% 10.45% and 9.91%, respectively. The positive rate of rotavirus and stellate virus decreased year by year in 2013-2015, and the positive rate of norovirus and rotavirus increased year by year. The peaks of diarrhea virus detection were from May to July and from September to December. Infants under 5 years old were more susceptible to infection than other age groups. Conclusion rotavirus, norovirus and stellate virus are the main pathogenic viruses of infectious diarrhea in Xuzhou from 2013 to 2015. Etiological surveillance and disease surveillance and early warning should be strengthened, and effective prevention and control measures should be taken in time for key population and epidemic strains.
【作者單位】： 徐州市疾病預防控制中心;
【分類號】：R440;R512.5

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