本文選題：耐碳青霉烯肺炎克雷伯菌 + 醫(yī)院感染�。� 參考：《中華醫(yī)院感染學(xué)雜志》2017年12期

【摘要】：目的通過耐碳青霉烯類肺炎克雷伯菌(CRKP)醫(yī)院感染的趨勢,了解醫(yī)院CRKP感染特點(diǎn)與變化,為CRKP醫(yī)院感染預(yù)防控制提供依據(jù)。方法前瞻性調(diào)查2011年1月-2016年12月入住某三甲綜合醫(yī)院患者429 933例,采用統(tǒng)一調(diào)查方法收集臨床微生物檢驗(yàn)1 208株肺炎克雷伯菌陽性的患者病歷資料,并判定菌株的感染、定植與污染,分析CRKP檢出率和感染率變化趨勢。結(jié)果 2011年1月-2016年12月1131例次患者檢出肺炎克雷伯菌,其中162例次患者檢出CRKP,CRKP總檢出率為14.32%,其各年份檢出率總體上升,差異有統(tǒng)計(jì)學(xué)意義(P0.01);成人ICU的檢出率最高,為28.94%,上升也最為明顯,從2011年的2.13%上升至2016年的48.57%;162例次患者CRKP中定植59例次,占36.42%,社區(qū)感染54例次,占33.33%,醫(yī)院感染49例次,占30.24%;社區(qū)感染率從2011年的0.04‰上升至2016年的0.23‰,醫(yī)院感染萬日感染率也從0.13上升為0.27,社區(qū)感染上升幅度更大。結(jié)論 CRKP的感染率呈現(xiàn)逐年上升趨勢,其中社區(qū)感染和定植例次上升更為明顯,提高了CRKP醫(yī)院感染的預(yù)防控制難度。
[Abstract]:Objective to investigate the characteristics and changes of nosocomial CRKP infection through the trend of nosocomial infection of Klebsiella Carbicilli pneumonia, and to provide evidence for the prevention and control of CRKP nosocomial infection. Methods A prospective survey of 429,933 patients admitted to a three A General Hospital from January 2011 to December 2016 was carried out. The medical records of 1 208 strains of Klebsiella pneumoniae positive were collected by a unified investigation method, and the infection of the strains was determined. The detection rate of CRKP and the trend of infection rate were analyzed. Results from January 2011 to December 2016, 1131 cases of Klebsiella pneumoniae were detected, of which the total rate of detection of CRKP- CRKP in 162 cases was 14.322.The detection rate of CRKP- CRKP increased in all years, and the difference was statistically significant (P 0.01), the detection rate of adult ICU was the highest. From 2.13% in 2011 to 48.57% in 2016, 59 cases (36.4222) were colonized, 54 cases (33.3333) of community infections, 49 cases of hospital infections (30.24 鈥，

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