本文選題：帶狀皰疹 + 感染�。� 參考：《中華醫(yī)院感染學雜志》2017年09期

【摘要】：目的分析帶狀皰疹繼發(fā)感染的病原學特點及危險因素,為臨床預(yù)防和治療提供參考依據(jù)。方法選取醫(yī)院2014年12月-2016年9月收治的帶狀皰疹患者953例,統(tǒng)計病原菌分布及分析帶狀皰疹繼發(fā)感染的危險因素。結(jié)果 87例帶狀皰疹繼發(fā)感染患者共分離培養(yǎng)出病原菌84株,其中革蘭陰性菌64株占76.2%,革蘭陽性菌17株占20.2%,真菌3株占3.6%;肺炎克雷伯菌對慶大霉素、阿米卡星、美羅培南耐藥率分別為85.7%、80.9%、95.2%,銅綠假單胞菌對慶大霉素、阿米卡星、美羅培南耐藥率分別為66.7%、83.3%、88.9%,大腸埃希菌對慶大霉素、阿米卡星、美羅培南耐藥率分別為60.0%、93.3%、100.0%,表皮葡萄球菌對紅霉素、青霉素、萬古霉素耐藥率分別為83.3%、66.7%、66.7%,金黃色葡萄球菌對紅霉素、青霉素、萬古霉素耐藥率分別為80.0%、80.0%、60.0%,凝固酶陰性葡萄球菌對紅霉素、青霉素、萬古霉素耐藥率分別為80.0%、60.0%、100.0%;單因素分析顯示,帶狀皰疹繼發(fā)感染與年齡≥50歲、皮損面積≥500cm2、未接受規(guī)范治療及有水痘帶狀皰疹病毒接觸史具有相關(guān)性(P0.05);多因素logistic回歸分析結(jié)果顯示,年齡≥50歲、皮損面積≥500cm2、未接受規(guī)范治療為帶狀皰疹繼發(fā)感染的獨立危險因素。結(jié)論革蘭陰性菌為帶狀皰疹繼發(fā)感染的主要病原菌,年齡≥50歲、皮損面積≥500cm2、未接受規(guī)范治療為帶狀皰疹繼發(fā)感染的危險因素,針對病原菌特點和危險因素,采取相應(yīng)措施,是降低帶狀皰疹繼發(fā)感染的關(guān)鍵。
[Abstract]:Objective to analyze the etiological characteristics and risk factors of herpes zoster secondary infection and to provide reference for clinical prevention and treatment. Methods 953 patients with herpes zoster were selected from December 2014 to September 2016. The distribution of pathogenic bacteria and the risk factors of secondary infection of herpes zoster were analyzed. Results A total of 84 strains of pathogenic bacteria were isolated from 87 patients with secondary infection of herpes zoster, of which 64 were Gram-negative bacteria (76.2B), 17 Gram-positive bacteria (20.2B), 3 fungi (3.6B), and Klebsiella pneumoniae (Klebsiella pneumoniae) against gentamicin and amikacin. The resistance rates of meropenem to gentamicin, amikacin and meropenem were 85.7% and 80.9%, respectively. The resistance rates of Pseudomonas aeruginosa to gentamicin, amikacin and meropenem were 66.7%, 83.3% and 88.9% respectively. The resistance rates of Escherichia coli to gentamicin, amikacin and meropenem were 60.093.93% and 100.0%, respectively, and those of Staphylococcus epidermidis to erythromycin. The drug resistance rates of Staphylococcus aureus to erythromycin, penicillin, vancomycin and vancomycin were 80.0 and 80.060.0.The coagulase-negative staphylococci were resistant to erythromycin and penicillin, respectively. The rates of vancomycin resistance were 80. 0% and 60. 0% respectively. Univariate analysis showed that herpes zoster secondary infection and age 鈮，

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