發(fā)布時間：2018-05-03 10:45

  本文選題：耐碳青霉烯鮑氏不動桿菌 + 暴發(fā)�。� 參考：《中華醫(yī)院感染學(xué)雜志》2017年18期

【摘要】：目的對神經(jīng)內(nèi)科ICU患者耐碳青霉烯鮑氏不動桿菌感染事件進行調(diào)查與控制,為臨床多藥耐藥菌預(yù)防控制提供參考。方法對2017年2月27日-2017年3月10日神經(jīng)內(nèi)科ICU 4例耐碳青霉烯鮑氏不動桿菌感染患者進行流行病學(xué)調(diào)查,采用環(huán)境生物學(xué)監(jiān)測方法采集標(biāo)本124份,其中空氣21份,物體表面87份,醫(yī)務(wù)人員手部6份、鼻腔6份、工作服4份,查找環(huán)境中的鮑氏不動桿菌,Eric(腸桿菌基因間重復(fù)共有序列)-PCR和多位點序列分型(MLST)分析患者分離的菌株與環(huán)境中菌株的同源性。結(jié)果 Eric-PCR和MLST結(jié)果顯示4名患者的痰液標(biāo)本中檢出2種基因型鮑氏不動桿菌,分別為ST92型和ST75型,其中1床和12床患者臨床菌株具有同源性,09床和19床患者臨床菌株具有同源性;6份物體表面標(biāo)本檢出鮑氏不動桿菌,分別為鼻飼碗、床沿、護理人員工作服,其中12床鼻飼碗,09、19床床沿,護理人員工作服上檢出的鮑氏不動桿菌與12床患者痰液標(biāo)本中的鮑氏不動桿菌屬于同一基因型。結(jié)論環(huán)境物體表面的消毒、手衛(wèi)生和隔離措施的缺失是此次多藥耐藥菌傳播的環(huán)節(jié),在多藥耐藥菌患者的診療過程中應(yīng)當(dāng)重視消毒隔離措施的執(zhí)行。
[Abstract]:Objective to investigate and control the infection of acinetobacter baumannii in patients with ICU in neurology department, and to provide reference for the prevention and control of multidrug resistant bacteria. Methods from February 27, 2017 to March 10, 2017, four patients with Acinetobacter baumannii infection in Department of Neurology, Department of Neurology, were investigated by epidemiology. 124 samples were collected by environmental biological monitoring method, among which 21 were airborne. 87 surfaces, 6 hands, 6 nasal passages, 4 overalls, To find Acinetobacter baumannii (Acinetobacter baumannii) in the environment (Enterobacter baumannii repeat common sequence-PCR and multilocus sequence typing) to analyze the homology between the strains isolated from patients and the strains in the environment. Results the results of Eric-PCR and MLST showed that two genotypes of Acinetobacter baumannii were found in sputum samples of 4 patients. They were ST92 type and ST75 type respectively. Acinetobacter baumannii was found in 1 bed and 12 beds of clinical strains in 9 beds and 19 beds in 6 samples of object surface, which were nasal feeding bowls, bedsides, and nursing staff overalls, respectively. Acinetobacter baumannii detected on the working clothes of nursing staff and Acinetobacter baumannii in sputum of 12 beds belonged to the same genotype. Conclusion Disinfection, hand hygiene and lack of isolation measures on the surface of environmental objects are the links of the transmission of multidrug resistant bacteria. The execution of disinfection and isolation measures should be paid more attention to in the diagnosis and treatment of patients with multidrug resistance bacteria.
【作者單位】： 南昌大學(xué)第一附屬醫(yī)院醫(yī)院感染管理科;
【基金】：江西省科技廳重點基金資助項目(20152ACG70015)
【分類號】：R516

【相似文獻】

相關(guān)期刊論文 前10條

1 徐二鵬;;鮑氏不動桿菌感染及護理措施研究進展[J];當(dāng)代醫(yī)學(xué)(學(xué)術(shù)版);2008年05期

2 盧健聰;蔡紹曦;耿穗娜;佟萬成;馬真;孟瑩;劉來昱;;2005-2007年鮑氏不動桿菌院內(nèi)下呼吸道感染的流行特征分析[J];中華醫(yī)院感染學(xué)雜志;2009年06期

3 何炳福;金法祥;楊越明;;老年患者肺部感染鮑氏不動桿菌的臨床及耐藥研究[J];中華醫(yī)院感染學(xué)雜志;2009年06期

4 周泓羽;袁U，

本文編號：1838188