重型病毒型肝炎患者醫(yī)院感染危險(xiǎn)因素研究
本文選題:重型病毒型肝炎 + 病原菌; 參考:《中華醫(yī)院感染學(xué)雜志》2015年16期
【摘要】:目的探討重型病毒型肝炎患者醫(yī)院感染病原菌分布、感染部位及危險(xiǎn)因素,為臨床重型病毒型肝炎醫(yī)院感染預(yù)防控制提供依據(jù)。方法回顧性分析2006年1月-2014年1月醫(yī)院收治的340例重型病毒型肝炎患者臨床資料,分析發(fā)生感染患者的病原菌及感染因素,數(shù)據(jù)采用SPSS 18.0軟件進(jìn)行統(tǒng)計(jì)分析。結(jié)果共發(fā)生醫(yī)院感染160例,感染率47.06%;檢出病原菌主要有白色假絲酵母菌、大腸埃希菌、銅綠假單胞菌、肺炎克雷伯菌及金黃色葡萄球菌,分別占32.92%、27.08%、21.25%、13.75%、5.00%;logistic回歸多因素分析結(jié)果顯示,年齡、肝硬化、應(yīng)用抗菌藥物、免疫功能低下及侵入性操作均為重型病毒型肝炎患者發(fā)生醫(yī)院感染的獨(dú)立危險(xiǎn)因素(P0.05)。結(jié)論重型病毒型肝炎患者醫(yī)院感染的發(fā)生率高、病原菌種類多、感染部位廣,臨床治療過程中應(yīng)根據(jù)相應(yīng)的危險(xiǎn)因素規(guī)范操作避免感染的發(fā)生。
[Abstract]:Objective to investigate the distribution of pathogenic bacteria, infection site and risk factors of nosocomial infection in patients with severe viral hepatitis, and to provide evidence for the prevention and control of nosocomial infection in patients with severe viral hepatitis. Methods the clinical data of 340 patients with severe viral hepatitis from January 2006 to January 2014 were analyzed retrospectively. The pathogenic bacteria and infection factors were analyzed. The data were analyzed by SPSS 18.0 software. Results there were 160 cases of nosocomial infection, the infection rate was 47.060.The main pathogenic bacteria were Candida albicans, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus, which accounted for 32.922,27.080.21.250.13.755.000.The results of logistic regression analysis showed that the main pathogens were Candida albicans, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus, respectively. Age, cirrhosis, antimicrobial use, low immune function and invasive operation were all independent risk factors for nosocomial infection in patients with severe viral hepatitis. Conclusion the incidence of nosocomial infection in patients with severe viral hepatitis is high, there are many kinds of pathogenic bacteria, and the sites of infection are wide. In the course of clinical treatment, the occurrence of infection should be avoided according to the corresponding risk factors.
【作者單位】: 山東省費(fèi)縣人民醫(yī)院感染科;山東省費(fèi)縣人民醫(yī)院檢驗(yàn)科;河北醫(yī)科大學(xué)第三醫(yī)院手外科;
【基金】:河北衛(wèi)生廳重點(diǎn)科技研究基金資助項(xiàng)目(20120341)
【分類號(hào)】:R512.6
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本文編號(hào):1822013
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