本文選題：艾滋病　切入點：單陽配偶　出處：《現(xiàn)代預(yù)防醫(yī)學(xué)》2017年07期

【摘要】：目的了解艾滋病配偶間HIV的傳播并探討其相關(guān)影響因素。方法采取動態(tài)隊列研究的方法,通過現(xiàn)場招募百色市202對艾滋病單陽配偶為研究對象,每6個月對患者進行一次隨訪并對其陰性的配偶進行HIV檢測,運用100人年陽轉(zhuǎn)率來計算配偶間HIV的傳播率,Kaplan-Meier分析HIV陰性的配偶仍保持陰性的概率,含依時協(xié)變量COX比例風(fēng)險模型分析配偶間HIV傳播的相關(guān)影響因素。結(jié)果單陽配偶中HIV患者平均年齡37.66±11.61歲,基線CD_4~+♂計數(shù)均值314.30±215.99個/mm~3,中位隨訪時間35個月(IQR:16-52),患者以男性、45歲以下、壯族、初中文化、農(nóng)民及農(nóng)民工、農(nóng)村居住和異性性途徑感染為主。隨訪期間共計14例陰性配偶發(fā)生了HIV陽轉(zhuǎn),陽轉(zhuǎn)率為2.21/100人年,配偶1~6年累積HIV陽轉(zhuǎn)率分別為2.11%、5.29%、7.75%、8.92%、8.92%、12.88%。經(jīng)含依時協(xié)變量COX比例風(fēng)險模型分析結(jié)果顯示,患者職業(yè)(AHR=16.28,95%CI:1.47-180.33)、配偶結(jié)果告知時間(AHR=0.10,95%CI:0.02-0.57)和安全套使用頻率(AHR=0.02,95%CI:0.00-0.19)與配偶間HIV傳播存在統(tǒng)計學(xué)關(guān)聯(lián),患者經(jīng)HIV確診后6個月Qg及時告知配偶結(jié)果的HIV傳播風(fēng)險降低了90%,配偶性行為時每次均使用安全套的HIV傳播風(fēng)險則減少了98%。結(jié)論加強咨詢檢測服務(wù),及時告知配偶HIV檢測結(jié)果,發(fā)生性行為時堅持正確使用安全套,可有利于預(yù)防配偶間經(jīng)性傳播HIV。
[Abstract]:Objective to understand the HIV transmission between spouses of HIV and discuss the related factors. Methods the dynamic cohort study, through on-site recruitment Baise 202 of HIV positive spouses as the research object, once every 6 months follow-up of patients and the negative spouses of HIV detection, using the spread of 100 person years of seroconversion to calculate the rate of spouse rate of HIV, Kaplan-Meier of HIV negative spouses remain negative probability, containing time-dependent covariate COX proportional hazard model analysis of the influence factors of HIV transmission between spouses. The results of the single spouse in HIV patients with a mean age of 37.66 + 11.61 years, baseline CD_4~+ male count average of 314.30 + 215.99 /mm~3, the median follow-up time was 35 months (IQR:16-52), with 45 years of age, male, Zhuang, junior middle school education, farmers and migrant workers, rural living and heterosexual infection. During the follow-up period, a total of 14 cases. The spouse had HIV seroconversion, seroconversion rate was 2.21/100 years, 1~6 years cumulative spouse HIV seroconversion rates were 2.11%, 5.29%, 7.75%, 8.92%, 8.92%, 12.88%. after covariates COX proportional hazard model analysis showed that in time, patient occupation (AHR=16.28,95%CI:1.47-180.33), the spouse (AHR=0.10,95%CI:0.02-0.57) and the time of disclosure condom use frequency (AHR=0.02,95%CI:0.00-0.19) were significantly associated with the HIV transmission between spouses, with risk of transmitting HIV HIV 6 months after diagnosis of Qg results promptly inform the spouse is reduced by 90%, the spread of HIV risk behavior of spouse when using condoms every time was decreased by 98%. conclusion to strengthen counseling and testing services, HIV test results promptly inform the spouse during sex, adhere to the correct use of condoms, which is conducive to the prevention of sexual transmission between spouses HIV.

【作者單位】： 百色市疾病預(yù)防控制中心;百色市衛(wèi)生監(jiān)督所;右江民族醫(yī)學(xué)院公共衛(wèi)生與管理學(xué)院;
【基金】：百色市科技計劃項目(百科計140801-3)
【分類號】：R512.91;R181.3

【相似文獻】

相關(guān)期刊論文 前2條

1 溫寧;HIV傳播途徑及機制[J];中國預(yù)防醫(yī)學(xué)雜志;2003年01期

2 ;[J];;年期

，

本文編號：1710777