本文選題：HIV感染　切入點：輸血傳播　出處：《中國輸血雜志》2015年08期

【摘要】：目的為阻斷經(jīng)輸血傳播HIV,提升浙江省血液安全水準(zhǔn)。方法自2011年開展阻斷經(jīng)輸血傳播HIV項目,針對輸血過程從血管到血管之不同階段,采用系統(tǒng)性綜合措施,包括前期的加強(qiáng)主動退出與保密性棄血、中期的推廣血篩核酸檢測和亞甲藍(lán)血漿病毒滅活、后期的推進(jìn)臨床科學(xué)合理用血之自體輸血。結(jié)果項目開展4年來,全省獻(xiàn)血者中確認(rèn)HIV感染快速上升趨勢較前被明顯遏制(P0.05),血液核酸篩查覆蓋從2011年26.5%至2014年達(dá)51.2%,開展血漿病毒滅活工作血站明顯增加,75%(9/12)血站其自體輸血占臨床用血5%,全省血液安全得以保障。結(jié)論阻斷經(jīng)輸血傳播HIV是一系統(tǒng)性綜合舉措開展以來全省未見輸血感染HIV案例,血液安全水準(zhǔn)明顯提升。項目成果需持久的維護(hù)、推進(jìn)和創(chuàng)新。
[Abstract]:Objective to prevent the transmission of HIV through blood transfusion and to raise the level of blood safety in Zhejiang Province.Methods the HIV project of blocking blood transfusion transmission was carried out in 2011. Systemic and comprehensive measures were adopted for different stages of blood transfusion from blood vessels to blood vessels, including early active withdrawal and confidentiality rejection.In the middle stage, sieve nucleic acid detection and methylene blue plasma virus inactivation were popularized, and autologous blood transfusion was carried out in the later stage.As a result, in the four years since the project began,Among the blood donors in the province, the rapid rising trend of HIV infection was significantly curbed. The nucleic acid screening coverage reached 51.2% from 2011 to 2014. The number of blood stations carrying out plasma virus inactivation work was significantly increased by 7575% 9 / 12). Autologous blood transfusion accounted for the clinical use at blood stations.Blood 5, the whole province blood security can be guaranteed.Conclusion there are no cases of blood transfusion infection with HIV in the whole province since the interruption of transfusion-transmitted HIV was carried out, and the blood safety level was improved obviously.Project results require sustained maintenance, promotion and innovation.
【作者單位】： 浙江省血液中心衛(wèi)生部血液安全研究重點實驗室;金華市中心血站;衢州市中心血站;
【分類號】：R512.91;R457.1

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本文編號：1707046