發(fā)布時間：2018-03-24 08:10

  本文選題：手術(shù)　切入點：血吸蟲　出處：《中國地方病防治雜志》2017年06期

【摘要】：目的探討分析經(jīng)頸靜脈肝內(nèi)門腔分流術(shù)治療血吸蟲性肝硬化門脈高壓征療效。方法選擇2010年3月至2016年3月本院收治的血吸蟲性肝硬化門靜脈高壓征患者58例,采用經(jīng)頸靜脈肝內(nèi)門腔分流術(shù)(TIPS)治療,觀察手術(shù)臨床療效,并比較分析患者手術(shù)前后門脈壓力、門脈壓力梯度變、血清生化指標變化。結(jié)果本組58例患者中,均成功置入支架建立分流道,手術(shù)成功率為100.00%,隨訪期內(nèi),無患者死亡;患者術(shù)后門脈壓力及門脈壓力梯度均較術(shù)前顯著降低(P0.05);患者手術(shù)前后血小板計數(shù)、紅細胞計數(shù)、天冬氨酸轉(zhuǎn)氨酶、丙氨酸轉(zhuǎn)氨酶、血清肌酐、尿素氮以及總膽紅素水平均有顯著差異(P0.05);術(shù)后門脈壓力降低幅度0~25%患者肝性腦病發(fā)生率顯著高于門脈壓力降低幅度≥25%患者(P0.05);術(shù)后門脈壓力降低幅度與支架狹窄發(fā)生率無明顯相關(guān)(P0.05)。結(jié)論經(jīng)頸靜脈肝內(nèi)門腔分流術(shù)治療血吸蟲性肝硬化門脈高壓征具有著顯著的臨床療效,能夠有效降低降低機體門脈壓力及門脈壓力梯度,并改善患者機體生化指標,而術(shù)后門脈壓力降低幅度越低,術(shù)后肝性腦病發(fā)生率越高。
[Abstract]:Objective to investigate the curative effect of portal cavity shunt through jugular vein in the treatment of portal hypertension syndrome of schistosomiasis cirrhosis. Methods 58 patients with portal hypertension syndrome of schistosomiasis cirrhosis were selected from March 2010 to March 2016. Transjugular intrahepatic portal shunt (TIPS) was used to observe the clinical efficacy of the operation, and to compare and analyze the changes of portal pressure, portal pressure gradient and serum biochemical indexes before and after operation. The successful rate of operation was 100.00. no patient died during the follow-up period, the portal pressure and portal pressure gradient after operation were significantly lower than those before and after operation (P 0.05), the platelet count and erythrocyte count before and after operation. Aspartate transaminase, alanine aminotransferase, serum creatinine, There were significant differences in urea nitrogen and total bilirubin levels (P 0.05), the incidence of hepatic encephalopathy in patients with postoperative portal pressure reduction of 0% or 25% was significantly higher than that in patients with more than 25% reduction in portal pressure, and the extent of portal pressure reduction and stent stenosis after operation was significantly higher than that in patients with portal vein pressure 鈮，

本文編號：1657441