發(fā)布時間：2018-03-15 08:04

  本文選題：型糖尿病　切入點：肺炎克雷伯菌　出處：《中華醫(yī)院感染學(xué)雜志》2017年22期 　論文類型：期刊論文

【摘要】：目的探索2型糖尿病并發(fā)肺炎克雷伯菌感染致敗血癥的臨床特征與生存狀況。方法選取2013年1月-2016年12月醫(yī)院接受治療的114例肺炎克雷伯菌感染所導(dǎo)致的敗血癥患者為研究對象,將其中57例2型糖尿病患者設(shè)為試驗組,其余無2型糖尿病患者57例設(shè)為對照組,比較兩組患者血漿糖化血紅蛋白及白細(xì)胞水平、腎功能水平、預(yù)后不良發(fā)生率、并發(fā)癥、治愈率及病死率。結(jié)果試驗組患者的白細(xì)胞計數(shù)與對照組比較,差異無統(tǒng)計學(xué)意義;試驗組患者的糖化血紅蛋白水平低于對照組,差異有統(tǒng)計學(xué)意義(P0.05);試驗組重度腎功能障礙患者多于對照組,差異有統(tǒng)計學(xué)意義(P0.05);試驗組中所患膽道疾病、脂肪肝、腫瘤以及膿腫等并發(fā)癥的患者多于對照組,差異有統(tǒng)計學(xué)意義(P0.05);試驗組患者的治療結(jié)局不良發(fā)生率高于對照組,差異有統(tǒng)計學(xué)意義(P0.05);兩組患者治愈率比較,差異無統(tǒng)計學(xué)意義;試驗組患者病死率高于對照組,差異有統(tǒng)計學(xué)意義(P0.05)。結(jié)論 2型糖尿病并發(fā)肺炎克雷伯菌感染致敗血癥患者的臨床癥狀更為嚴(yán)重,易引發(fā)多種并發(fā)癥且死亡率較高,有效的臨床治療是解決預(yù)后問題的有效途徑。
[Abstract]:Objective to investigate the clinical features and survival status of septicemia caused by Klebsiella pneumoniae infection in type 2 diabetes mellitus. Methods 114 cases of septicemia caused by Klebsiella pneumoniae infection were selected from January 2013 to December 2016. The patient was the subject of the study. 57 patients with type 2 diabetes mellitus were divided into experimental group and 57 patients without type 2 diabetes mellitus as control group. Plasma glycosylated hemoglobin and leukocyte levels, renal function level, incidence of poor prognosis and complications were compared between the two groups. Results there was no significant difference in leukocyte count between the patients of the test group and the control group, and the level of glycosylated hemoglobin in the patients in the test group was lower than that in the control group. The difference was statistically significant (P 0.05); the number of patients with severe renal dysfunction in the trial group was more than that in the control group (P 0.05); the number of patients with biliary diseases, fatty liver, tumor and abscess in the trial group was more than that in the control group. The difference was statistically significant (P 0.05), the incidence of adverse outcome in the trial group was higher than that in the control group, and the difference was statistically significant (P 0.05). There was no significant difference in the cure rate between the two groups, and the mortality of the patients in the trial group was higher than that in the control group. Conclusion the clinical symptoms of patients with septicemia caused by Klebsiella pneumoniae infection in type 2 diabetes mellitus are more serious. Effective clinical treatment is an effective way to solve the problem of prognosis.
【作者單位】： 浙江中醫(yī)藥大學(xué);杭州市師范大學(xué)附屬醫(yī)院內(nèi)分泌科;杭州市師范大學(xué)附屬醫(yī)院呼吸科;
【分類號】：R515.3;R587.1

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