發(fā)布時間：2018-01-29 22:52

  本文關(guān)鍵詞： 重癥監(jiān)護病房 肺部真菌感染 危險因素　出處：《重慶醫(yī)科大學》2017年碩士論文　論文類型：學位論文

【摘要】：目的統(tǒng)計重癥監(jiān)護病房患者真菌感染的相關(guān)危險因素,探討重癥監(jiān)護病房(ICU)患者肺部真菌感染的臨床特點及相關(guān)危險因素,尋找預防肺部真菌感染的對策。方法回顧性分析2014年4月~2016年7月我院116例ICU肺部真菌感染患者臨床資料,并選擇同期入住ICU非真菌感染重癥肺炎患者110例作為對照組,數(shù)據(jù)采用SPSS 17.0統(tǒng)計軟件進行處理。結(jié)果ICU肺部真菌感染患者感染的癥狀、體征主要包括肺部濕Up音、發(fā)熱與痰量增多、黏稠等,其中以發(fā)熱為主;經(jīng)檢查共分離出126株真菌,其中真菌主要有光滑假絲酵母菌13株,熱帶假絲酵母菌21株,白色假絲酵母菌76株等;通過統(tǒng)計學推斷,引起肺部真菌感染的相關(guān)危險因素主要有入住ICU時間1周、白細胞小于4×109/L、低蛋白血癥、氣管插管與氣管切開、長期使用免疫抑制劑與糖皮質(zhì)激素、灌腸后大便3日未解、應(yīng)用≥2種廣譜高效抗菌藥物時間1周等。其中應(yīng)用≥2種廣譜高效抗菌藥物時間1周、灌腸后大便3日未解、低蛋白血癥、留置靜脈導管1周是獨立危險因素。結(jié)論ICU肺部真菌感染患者的癥狀、體征以發(fā)熱為主,真菌感染類型以白色假絲酵母菌最多,應(yīng)用≥2種廣譜高效抗菌藥物時間1周、灌腸后大便3日未解、低蛋白血癥、留置靜脈導管1周是獨立危險因素。
[Abstract]:Objective to analyze the risk factors of fungal infection in patients in intensive care unit (ICU), and to explore the clinical characteristics and related risk factors of fungal infection in lung of patients with ICU in intensive care unit (ICU). Methods the clinical data of 116 ICU patients with pulmonary fungal infection from April 2014 to July 2016 were retrospectively analyzed. 110 cases of severe pneumonia with ICU nonfungal infection were selected as control group. Results the symptoms and signs of pulmonary fungal infection in patients with ICU were mainly including lung wet up sound, fever and sputum volume increase, viscous and so on. Among them, fever is the main; A total of 126 fungi were isolated, of which 13 were Candida smooth, 21 were Candida tropicalis and 76 were Candida albicans. According to statistical analysis, the main risk factors for pulmonary fungal infection were ICU stay for 1 week, leukocyte less than 4 脳 109 / L, hypoproteinemia, tracheal intubation and tracheotomy. Immunosuppressive agents and glucocorticoids were used for a long time. After enema, defecation was not solved on 3rd, and the time of application of more than 2 broad-spectrum high effective antibiotics was 1 week, in which 鈮，

本文編號：1474562