The renin-angiotensin system(RAS)regulates vascular tone and plays a critical role in vascular remodeling,which is the result of a complex interplay of alterations in vascular tone and structure.Inhibition of the RAS has led to important pharmacological tools to prevent and treat vascular diseases such as hypertension,diabetic vasculopathy and atherosclerosis.Angiotensin converting enzyme 2(ACE2)was recently identified as a multifunctional monocarboxypeptidase responsible for the conversion of a...

【文章頁(yè)數(shù)】：7 頁(yè)

【文章目錄】：
1 ACE2/Ang-(1#7)signaling and vascular pro-liferation and hypertrophy
2 ACE2/Ang-(1#7)signaling and vascular in-flammation and oxidative stress
3 ACE2/Ang-(1#7)signaling and vascular fi-brosis
4 Conclusion and perspectives



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