本文選題：人早期胚胎　切入點：輔助生殖技術　出處：《第一軍醫(yī)大學》2005年碩士論文

【摘要】：目的:(1)探討多個原核期形態(tài)學指標與Day3(取卵后第三天)胚胎著床之間的關系,驗證并篩選能正確反映胚胎移植后種植潛能的原核期形態(tài)指標;(2)探討多個Day3胚胎形態(tài)學指標和胚胎著床的關系,篩選能正確反映胚胎移植后種植潛能的Day3胚胎形態(tài)指標;(3)根據(jù)篩選的原核期和Day3胚胎形態(tài)觀察指標,建立原核期胚胎評分、Day2(取卵后第二天)胚胎評分、Day3胚胎評分及Day3聯(lián)合原核綜合評分系統(tǒng)。 方法:前瞻性分析2004年10月～2005年1月,在南方醫(yī)院生殖醫(yī)學中心接受輔助生殖治療的166位不孕患者。(1)166位不孕患者中,選取年齡均≤35歲,HCG日子宮內膜厚度均≥8mm,且Day3進行胚胎移植后100%植入的共30個移植周期患者(56個胚胎,植入組),同時隨機選取滿足上述條件的100%未植入32個移植周期患者(64個胚胎,未植入組)。根據(jù)原核期形態(tài)包括兩原核是否相鄰、大小、居于胞漿中的位置,核仁前體(Nucleolar precursor bodies,NPB)的排列方式、大小、數(shù)目,極體是否完整,胞漿暈的有無,胞質顏色及顆粒是否正常,胞質內空泡的有無進行數(shù)據(jù)統(tǒng)計,比較原核期形態(tài)與胚胎種植成功與否之間的相關性。(2)相同62個移植周期患者,根據(jù)Day3胚胎形態(tài)包括卵裂球數(shù)目、卵裂球大小差異、卵裂球核、卵裂球顏色及顆粒、碎片比例和碎片類型、胞質內空泡、透明帶厚度及形狀方面進行數(shù)據(jù)統(tǒng)計,比較Day3胚胎形態(tài)與胚胎種植成功與否之間的相關性。(3)根據(jù)上述實驗結果,選取原核期兩原核形態(tài)、
[Abstract]:Objective to study the relationship between the morphological indices of multiple prokaryotes and embryo implantation in Day3 (the third day after oviposition).To verify and screen the prokaryote morphological index which can correctly reflect the implantation potential after embryo transfer, and to explore the relationship between multiple Day3 embryo morphological indexes and embryo implantation.The morphological index of Day3 embryos, which can correctly reflect the implantation potential after embryo transfer, was screened according to the prokaryote stage and the morphological observation index of Day3 embryos.The embryo scoring system of day 2 (the second day after oviposition) and the embryo score of day 3 and Day3 combined with prokaryotic evaluation were established.Methods: from October 2004 to January 2005, 166 infertile patients received adjuvant reproductive treatment in the Center of Reproductive Medicine of Southern Hospital.A total of 30 patients (56 embryos) with 100% Day3 implantation after embryo transfer were selected. The endometrial thickness was 鈮，

本文編號：1720928