巴貝蟲棒狀體蛋白的研究進(jìn)展
發(fā)布時間:2019-08-06 06:47
【摘要】:巴貝蟲是一類專性的細(xì)胞內(nèi)寄生的頂復(fù)門原蟲,是人和動物的重要病原。這類原蟲具有相似的亞細(xì)胞結(jié)構(gòu)并能分泌與入侵相關(guān)的保守蛋白,尤其是在入侵宿主細(xì)胞階段分泌的棒狀體相關(guān)蛋白被認(rèn)為是保護(hù)寄生蟲入侵和繁殖的關(guān)鍵分子,其在蟲體入侵的納蟲空泡形成過程中發(fā)揮重要作用。隨著基因組學(xué)和蛋白質(zhì)組學(xué)技術(shù)的不斷發(fā)展,其相關(guān)研究也越來越深入。因此,本文就目前研究較多的牛巴貝蟲、羊巴貝蟲、吉氏巴貝蟲、雙芽巴貝蟲和東方巴貝蟲等棒狀體相關(guān)蛋白的研究現(xiàn)狀進(jìn)行了綜述。
[Abstract]:Babella is a kind of specialized intracellular parasitic protozoa, which is an important pathogen of human and animal. This kind of protozoa has similar subcellular structure and can secrete conserved proteins related to invasion, especially rod-body related proteins secreted in the stage of invading host cells, which are considered to be the key molecules to protect parasite invasion and reproduction, and play an important role in the formation of vacuole in parasites invading. With the continuous development of genomics and proteome technology, its related research is becoming more and more in-depth. Therefore, in this paper, the research status of rod-body related proteins, such as Babella bovis, Babella sheep, Babella gibberelli, Babellaria dichotoma and Babella oriental, was reviewed in this paper, and the research status of rod-body related proteins was reviewed in this paper.
【作者單位】: 中國疾病預(yù)防控制中心寄生蟲病預(yù)防控制所 衛(wèi)生部寄生蟲病原與媒介生物學(xué)重點實驗室 世界衛(wèi)生組織熱帶病合作中心 國家級熱帶病國際聯(lián)合研究中心;
【基金】:公益性衛(wèi)生行業(yè)科研專項(201202019) 上海市衛(wèi)生計生委青年基金項目(20154Y0155)
【分類號】:R38
本文編號:2523380
[Abstract]:Babella is a kind of specialized intracellular parasitic protozoa, which is an important pathogen of human and animal. This kind of protozoa has similar subcellular structure and can secrete conserved proteins related to invasion, especially rod-body related proteins secreted in the stage of invading host cells, which are considered to be the key molecules to protect parasite invasion and reproduction, and play an important role in the formation of vacuole in parasites invading. With the continuous development of genomics and proteome technology, its related research is becoming more and more in-depth. Therefore, in this paper, the research status of rod-body related proteins, such as Babella bovis, Babella sheep, Babella gibberelli, Babellaria dichotoma and Babella oriental, was reviewed in this paper, and the research status of rod-body related proteins was reviewed in this paper.
【作者單位】: 中國疾病預(yù)防控制中心寄生蟲病預(yù)防控制所 衛(wèi)生部寄生蟲病原與媒介生物學(xué)重點實驗室 世界衛(wèi)生組織熱帶病合作中心 國家級熱帶病國際聯(lián)合研究中心;
【基金】:公益性衛(wèi)生行業(yè)科研專項(201202019) 上海市衛(wèi)生計生委青年基金項目(20154Y0155)
【分類號】:R38
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