本文選題：重復 + 骨生長盒　； 參考：《遵義醫(yī)學院》2011年碩士論文

【摘要】：目的：反復將預裝人工骨材料的骨生長檢測盒植入貴州小型豬體內(nèi),觀察檢測盒內(nèi)的骨生長情況,研究可重復使用的骨生長檢測盒觀測人工骨材料成骨能力的可行性。 方法：實驗組骨生長檢測盒內(nèi)芯雙腔均預裝人工骨材料的(n=8),對照組骨盒內(nèi)芯一側(cè)內(nèi)腔均預裝人工骨材料,其中另一側(cè)內(nèi)腔未填充人工骨材料的骨盒(n=4)為對照組1；其中另一側(cè)內(nèi)腔預裝明膠海棉的單腔骨盒為(n=4)為對照組2,植入貴州小型豬的股骨及脛骨干骺端,術(shù)后隔2月取出內(nèi)芯(共2次),換入新內(nèi)芯,對內(nèi)芯填充物行肉眼觀察、組織學觀察,比較填充物的成骨情況。 結(jié)果：術(shù)后2月,肉眼觀察實驗組內(nèi)芯內(nèi)腔見灰白色組織,對照組未預裝人工骨材料的內(nèi)芯內(nèi)腔見褐色組織：組織學觀察實驗組內(nèi)芯標本有大量骨組織生成,對照組未預裝人工骨材料的內(nèi)芯標本僅有纖維組織生成。 結(jié)論：可重復使用的骨生長檢測盒可用于觀察人工骨材料的成骨能力。
[Abstract]:Objective: to investigate the feasibility of bone growth test box which can be used to detect the osteogenic ability of artificial bone material in Guizhou miniature pig after implantation of bone growth test box with preloaded artificial bone material repeatedly to observe the bone growth situation in the test box and to study the feasibility of using reusable bone growth test box to observe the osteogenic ability of artificial bone material. Methods: in the experimental group, the inner core of the bone growth test box was preloaded with artificial bone material (N8), while in the control group, the artificial bone material was preloaded in one side of the inner core of the bone box, and the other side of the bone box (nd4) without artificial bone material was 1 in the control group. The single cavity bone box of preloaded gelatin sponge on the other side was the control group 2, implanted into the femur and tibial metaphysis of Guizhou miniature pig. The inner core (2 times) was taken out at 2 months after operation, and the new core was replaced with the new core, and the inner core filler was observed with the naked eye. Histological observation was performed to compare the osteogenesis of fillers. Results: two months after operation, grayish white tissue was observed in the inner core of the experimental group and brown tissue was observed in the inner core of the control group without artificial bone material. In the control group, only fibrous tissue was formed in the inner core specimens without artificial bone materials. Conclusion: the reusable bone growth test box can be used to observe the osteogenic ability of artificial bone.
【學位授予單位】：遵義醫(yī)學院
【學位級別】：碩士
【學位授予年份】：2011
【分類號】：R329

【參考文獻】

相關(guān)期刊論文 前1條

1 李雪盛;孫建軍;;脫細胞松質(zhì)骨復合骨形態(tài)發(fā)生蛋白2異位成骨的實驗研究[J];生物醫(yī)學工程與臨床;2009年04期

，

本文編號：2093808