抑郁傾向個體的負(fù)性記憶抑制
[Abstract]:Previous studies have shown that depressed individuals are often invaded and disturbed by unpleasant memories or thoughts, and their active inhibition of negative memory is impaired. In order to elucidate the neural mechanism of memory suppression in depressive patients, event-related potential (ERP) technique was used to investigate the memory suppression tasks of individuals with depression tendency at the coding and extraction stages. At the coding stage, the study investigated the directional forgetting effect and the corresponding electrophysiological activities of the subjects with high or low depression tendency on neutral and negative words. The results showed that the subjects with low depression tendency showed directional forgetting effect on both neutral and negative materials, while those with high depression tendency only had directional forgetting effect on neutral materials, and they had difficulty forgetting in negative materials. EEG results showed that compared with the low depression group, the subjects with high depression tendency produced larger P2 and LPP, when they watched the negative words passively, and produced larger P1 and N2 when they inhibited the encoding of negative materials. Together, these results suggest that individuals with a high tendency to depression have more selective attention and processing of negative materials at the primary stage of perception, while actively suppressing the coding of negative materials, although they call on more cognitive resources. Greater cognitive effort has been made, but they have failed, suggesting that they are less effective than normal in restraining control mechanisms. In the extraction stage, the behavioral scores and brain electrophysiological activities of subjects with high or low depression tendency were investigated by intentional extraction and inhibition of neutral and negative materials. The results showed that the subjects with high depression tendency showed a tendency of "mood consistency" in memory extraction: compared with the low depression group, The subjects with high depression tendency produced larger LPC, under recall negative memory condition and smaller N 2 under inhibition recall negative memory condition, indicating that they had active extraction advantage of negative memory and their pair had entered long. The negative information of time memory has lower inhibition motivation than normal people. Therefore, it is difficult to suppress the extraction of negative memory. Through the above two experiments, we found that in the coding stage, individuals with high depressive propensity were abnormal in the bottom-up selective attention and top-down inhibition control mechanism. And these two mechanisms together lead to their failure to suppress negative material coding. In the extraction stage, individuals with high depressive tendency had the advantage of extraction and inhibition of negative memory. It is this kind of abnormal memory coding and extraction that makes them tend to regurgitate continuously in their life, which makes it difficult to control themselves, thus further exacerbating the depressed mood and creating a vicious circle between negative emotion and negative ruminant. However, since the subjects selected in this study were individuals with a tendency to depression rather than clinically depressed patients, the findings should be extrapolated with caution.
【學(xué)位授予單位】:深圳大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2017
【分類號】:B842.3
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