【摘要】：目的:本課題是中醫(yī)正骨仿真訓練系統(tǒng)研究的子課題,主要研究將醫(yī)學圖像三維重建技術和有限元方法結合應用于正骨手法研究。首先建立正常肱骨三維有限元模型,驗證模型的有效性,再建立A3型肱骨骨干骨折三維有限元模型,并分析中醫(yī)正骨手法作用下骨折模型的生物力學改變,將手法操作過程中的力學特征進行數(shù)值化提取和分析,推測手法的作用機制。方法:選擇一位健康的青年男性志愿者,對其上肢自尺橈骨上端至肱骨頭進行連續(xù)斷層掃描,層厚設為2mm,共得到193張二維CT圖像。將CT數(shù)據導入MIMICS軟件中,通過圖像分割、三維重建、劃分網格和材料屬性賦值,構建正常肱骨有限元模型,利用ANSYS軟件進行力學分析,與文獻中肱骨的生物力學數(shù)據相比較,以此驗證模型的有效性。在正常肱骨模型上劃定骨折線,構建的A3型肱骨干骨折模型,結合ANSYS軟件對骨折模型進行手法模擬的應力應變分析。結果:利用MIMICS軟件實現(xiàn)了肱骨CT圖像的精確分割,建立了正常肱骨和A3型肱骨干骨折三維模型,對幾何模型劃分網格,并按均勻賦值法賦予骨骼材料屬性,轉化成有限元模型。利用ANSYS軟件,對模型加載載荷,模擬生物力學實驗和中醫(yī)正骨手法,驗證了模型的有效性,并分析了手法的力學特征。結論:將醫(yī)學圖像三維重建技術和有限元分析方法應用于中醫(yī)正骨手法的力學研究是可行的。課題建立的正常肱骨和肱骨干骨折模型,不僅外形細膩逼真,而且經驗證其物理特性與真實人體骨骼相接近,能夠很好地反映骨骼的力學變化,實現(xiàn)手法的定量分析,有利于推測作用機制。后續(xù)研究中,將增加肌肉組織的模擬和實體生物力學實驗做對比分析,增加結果的可靠性。
[Abstract]:Objective: this subject is a sub-subject of Chinese medicine orthopedic bone simulation training system. It mainly studies the application of 3D reconstruction technology of medical image and finite element method to orthopaedic manipulations. Firstly, the normal three-dimensional finite element model of humerus was established to verify the validity of the model, and then the three-dimensional finite element model of A3 type fracture of humeral shaft was established, and the biomechanical changes of the fracture model under the action of orthopaedic manipulation of traditional Chinese medicine were analyzed. The mechanical characteristics of manipulation were extracted and analyzed numerically, and the mechanism of manipulation was speculated. Methods: a healthy young male volunteer was selected and his upper limb was scanned continuously from the upper end of the ulna and radius to the head of the humerus. The slice thickness was 2 mm. A total of 193 2D CT images were obtained. The CT data was introduced into MIMICS software. The normal humeral finite element model was constructed by image segmentation, 3D reconstruction, meshing and material attribute assignment. The mechanical analysis of the normal humerus was carried out by using ANSYS software. The results were compared with the biomechanical data of humerus in the literature. The validity of the model is verified. The fracture line was delineated on the normal humeral model and the A3 type humeral shaft fracture model was constructed. The stress and strain analysis of manual simulation of the fracture model was carried out with ANSYS software. Results: the accurate segmentation of humeral CT images was realized by using MIMICS software. The 3D models of normal humerus and A3 type humeral shaft fractures were established. The geometric models were meshed, and the properties of bone materials were assigned according to the uniform assignment method, and the finite element model was transformed into a finite element model. The ANSYS software was used to load the model, simulate the biomechanics experiment and traditional Chinese medicine orthopaedic manipulation to verify the validity of the model, and analyze the mechanical characteristics of the manipulation. Conclusion: it is feasible to apply three-dimensional medical image reconstruction and finite element analysis to the mechanical study of orthopaedic manipulation in traditional Chinese medicine. The model of normal humerus and humeral shaft fracture established by the subject not only has fine and realistic appearance, but also has been proved to be close to the real human skeleton, which can well reflect the mechanical changes of bone and realize the quantitative analysis of manipulations. It is helpful to speculate the mechanism of action. In the follow-up study, the simulation of muscle tissue and the physical biomechanical experiment will be compared and analyzed to increase the reliability of the results.
【學位授予單位】：山東中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2016
【分類號】：R274

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