【摘要】：目的:回顧、總結(jié)惡性腫瘤的中西醫(yī)學(xué)病因病機(jī)、治療原則、治療方法,總結(jié)周文波主任治療惡性腫瘤(腎陽虧虛型)的學(xué)術(shù)思想及經(jīng)驗(yàn),探討其辨證思路及用藥規(guī)律,為繼承資深老中醫(yī)治療惡性腫瘤的寶貴經(jīng)驗(yàn),提供第一手臨床資料,為臨床治療惡性腫瘤提供新思路。臨床資料與方法:以2015年6月——2016年1月期間在遼寧省中醫(yī)研究院腫瘤科門診求治的67名(腎陽虧虛型)患者為臨床觀察對(duì)象,以周文波主任自擬的扶陽一號(hào)方為基本方治療,7天為一個(gè)療程,連續(xù)服用4個(gè)療程,并進(jìn)行心理疏導(dǎo),同時(shí)囑患者日一次自行艾灸關(guān)元、神闕、命門穴位,以皮膚潮紅為度,大約20分鐘。每個(gè)療程后記錄并統(tǒng)計(jì)患者生存質(zhì)量評(píng)分、KPS評(píng)分。治療結(jié)束一個(gè)月后隨訪。4個(gè)療程后,將數(shù)據(jù)進(jìn)行統(tǒng)一整理,對(duì)患者生存質(zhì)量評(píng)分、KPS評(píng)分進(jìn)行評(píng)估,運(yùn)用spss17.0統(tǒng)計(jì)軟件進(jìn)行統(tǒng)計(jì)學(xué)分析,客觀地評(píng)價(jià)治療后的臨床療效。結(jié)果:統(tǒng)計(jì)結(jié)果表明:經(jīng)過四個(gè)療程的治療后,67例患者(腎陽虧虛型)的KPS及QOL評(píng)分均較治療前升高,其中治療后第二周、第三周、第四周的KPS評(píng)分分別為56.36±7.48、58.68±7.86、61.43±8.29,與治療前比較有明顯差異(P0.05),治療結(jié)束一個(gè)月后隨訪,KPS評(píng)分為69.47±9.13,與治療前比較有顯著性差異(P0.01)。治療后第二周、第三周、第四周的QOL評(píng)分分別為28.36±3.71、30.13±4.09、32.58±4.33,與治療前比較有明顯差異(P0.05),經(jīng)過四個(gè)療程的治療結(jié)束一個(gè)月后,再次隨訪,所記錄的QOL評(píng)分為39.09±5.38,與治療前比較有顯著性差異(P0.01)。結(jié)論:腎陽虧虛型腫瘤多是在陽氣耗散枯竭、陰陽交感缺失、陽氣不能制約陰形的前提下導(dǎo)致的“陰陽離絕之勢”。扶陽法具有補(bǔ)腎益陽、鎮(zhèn)靜安神等作用,通過扶助陽氣,使陽氣在衛(wèi)外過程中,通過陰陽交感、產(chǎn)生精微物質(zhì),藏于體內(nèi),發(fā)揮治療和防御惡性腫瘤的作用。藥物、艾灸治療的同時(shí),臨床還注重心理疏導(dǎo),緩解患者恐懼、焦慮、抑郁的情緒。使患者陽氣漸復(fù),體質(zhì)改善,對(duì)于提高患者生存質(zhì)量,具有理想的臨床療效。
[Abstract]:Objective: to review and summarize the etiology, pathogenesis, treatment principles and treatment methods of malignant tumors in Chinese and western medicine, summarize the academic thoughts and experiences of Director Zhou Wenbo in the treatment of malignant tumors (deficiency of kidney yang), and discuss its dialectical thinking and drug use law. In order to inherit the valuable experience of senior traditional Chinese medicine in the treatment of malignant tumors, to provide first-hand clinical data, and to provide new ideas for clinical treatment of malignant tumors. Clinical data and methods: from June 2015 to January 2016, 67 patients (deficiency of Kidney Yang) seeking treatment in oncology department of Liaoning Academy of traditional Chinese Medicine were selected as clinical observation objects. Taking the Fuyang No. 1 prescription prepared by Director Zhou Wenbo as the basic prescription for 7 days as a course of treatment, taking four consecutive courses of treatment, and conducting psychological counseling, the patient was told to moxify Guanyuan, Shenque, Mingmen acupoints once a day, with the degree of redness to the skin. About twenty minutes. The quality of life score (QOL) and KPS score were recorded and counted after each course of treatment. Four courses of treatment were followed up after the end of the treatment. After 4 courses of treatment, the data were unified to evaluate the patients' quality of life score (QOL) and KPS score. The statistical analysis was carried out by using spss17.0 statistical software to objectively evaluate the clinical effect after the treatment. Results: after four courses of treatment, the scores of KPS and QOL in 67 patients (deficiency of kidney-yang) were higher than those before treatment, including the second and third weeks after treatment. In the fourth week, the KPS scores were 56.36 鹵7.48 鹵58.68 鹵7.86 鹵61.43 鹵8.29, which were significantly different from those before treatment (P0.05), and the follow-up scores of one month after treatment were 69.47 鹵9.13, which were significantly different from those before treatment (P0.01). The QOL scores of the second week, the third week and the fourth week after treatment were 28.36 鹵3.71 鹵30.13 鹵4.09 鹵32.58 鹵4.33, respectively, which were significantly different from those before treatment (P0.05). After a month of follow-up after four courses of treatment, the QOL score recorded was 39.09 鹵5.38, which was significantly different from that before treatment (P0.01). Conclusion: most tumors of deficiency of kidney-yang are caused by the depletion of Yang qi, the deficiency of synaesthesia of yin and yang, and the fact that yang qi can not restrict the Yin shape. Fuyang method has the functions of tonifying the kidney and supplementing yang, calming and calming the mind, and so on. It helps Yang Qi to produce subtle substances in the process of protecting and protecting outside the health, and produces subtle substances, which are hidden in the body and play a role in treating and defending malignant tumors. Medicine, moxibustion treatment, clinical also pay attention to psychological guidance, ease the patient's fear, anxiety, depression mood. It is an ideal clinical effect to improve the quality of life of patients by gradually recovering yang qi and improving their physique.
【學(xué)位授予單位】：遼寧中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R249;R273
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本文編號(hào)：2203054