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新疆喀什地區(qū)西北燥證對慢性阻塞性肺疾病的影響

發(fā)布時間:2018-08-06 09:45
【摘要】:目的:通過問卷調查,明確新疆喀什地區(qū)不同民族慢阻肺患者西北燥證的罹患情況,探討西北燥證對新疆喀什地區(qū)慢阻肺患者病情及證情的影響,以期為慢性阻塞性肺疾病的高危人群篩查,以及中西醫(yī)結合臨床干預提供理論依據(jù)。方法:調查研究喀什地區(qū)第一、第二人民醫(yī)院明確診斷為慢阻肺的患者及喀什地區(qū)各社區(qū)門診未患有相關疾病且民族、性別相同、年齡相當?shù)慕】稻用癜l(fā)放西北燥證調查量表進行調查并收回,對兩組數(shù)據(jù)進行病例對照研究及統(tǒng)計分析,發(fā)現(xiàn)兩組數(shù)據(jù)的差異性,明確西北燥證對新疆喀什地區(qū)慢阻肺的影響作用。結果:(1)慢阻肺組漢族男性與女性西北燥證患病情況均高于對照組,且慢阻肺組漢族女性西北燥證患病率顯著高于男性;在慢阻肺患者中維吾爾族男性與女性西北燥證患病情況明顯高于非西北燥證患病者,且維吾爾族女性西北燥證患病率顯著高于本民族男性。同時西北燥證對慢阻肺的發(fā)病存在民族差異性,慢阻肺患者中漢族罹患西北燥證的情況高于維吾爾族。(2)西北燥證對COPD的相對危險度OR值為8.11,慢阻肺組西北燥證患者西醫(yī)病情積分與西醫(yī)證情指數(shù)明顯高于未患西北燥證者,慢阻肺病情嚴重程度受西北燥證的影響作用明顯。(3)慢阻肺組肺衛(wèi)孔竅皮膚燥證與肝腎精血不足證患病程度明顯于對照組。研究發(fā)現(xiàn)肺衛(wèi)孔竅皮膚燥證為漢族慢阻肺患者西北燥證患病的主要表現(xiàn)特點,而脾胃蘊濕證為維吾爾族慢阻肺患者的主要表現(xiàn)特點。女性西北燥證患者主要證候表現(xiàn)為肝腎精血不足證。(4)慢阻肺患者中西北燥證患病者虛證以氣虛證表現(xiàn)明顯,陰虛證表現(xiàn)次之。慢阻肺患者中維吾爾族陰虛證及氣虛證的患病嚴重程度均高于漢族,其女性患者的陰虛證、氣虛證罹患嚴重程度均高于男性,男性陽虛證患病嚴重程度高于女性。結論:慢阻肺患者中,女性受西北燥證影響的程度大于男性,漢族較維吾爾族更易罹患西北燥證;肺衛(wèi)孔竅皮膚燥證為漢族西北燥證患病的主要表現(xiàn)特點,脾胃蘊濕證為維吾爾族患者的主要表現(xiàn)特點。女性患者主要證候特點為肝腎精血不足證。肺衛(wèi)孔竅皮膚燥證、肝腎精血不足證與新疆喀什地區(qū)COPD穩(wěn)定期中醫(yī)證候關系最緊密。慢阻肺患者中,西北燥證患者虛證以氣虛證多見,陰虛證次之;維吾爾族氣虛及陰虛證均比漢族嚴重;女性患者虛證證候以氣虛證和陰虛證為主要表現(xiàn),男性則以陽虛證為主要證候。
[Abstract]:Objective: to investigate the attack status of northwest dryness syndrome of different nationalities in Kashi area of Xinjiang by questionnaire, and to explore the influence of northwest dryness syndrome on the condition and syndromes of chronic obstructive lung patients in Kashi area of Xinjiang. In order to provide theoretical basis for high-risk screening of chronic obstructive pulmonary disease and clinical intervention of integrated Chinese and western medicine. Methods: the first and second people's Hospital in Kashi area were investigated. The patients diagnosed as COPD and the outpatients of each community in Kashi area were not suffering from related diseases and had the same gender. The healthy residents of the same age issued the Northwest dryness Survey scale to investigate and retract it. The data of the two groups were analyzed by case-control study and statistical analysis, and the differences between the two groups of data were found. The effect of northwest dryness syndrome on chronic obstructive lung in Kashi area of Xinjiang was clarified. Results: (1) the prevalence rate of northwest dryness syndrome in Han nationality and female in COPD group was higher than that in control group, and the prevalence rate of northwest dryness syndrome was significantly higher in COPD group than in male. The prevalence of northwest dryness in Uygur and female was significantly higher than that in non-northwest dryness, and the prevalence of northwest dryness in Uygur women was significantly higher than that in male. At the same time, the Northwest dryness Syndrome has national differences in the pathogenesis of COPD. The incidence of northwest dryness syndrome was higher in Han nationality than that in Uygur nationality. (2) the OR value of northwest dryness syndrome to COPD was 8.11. The scores of western medicine disease and western medicine syndrome information index of patients with northwest dryness syndrome in chronic obstructive lung group were significantly higher than those without northwest dryness syndrome. The severity of chronic obstructive pulmonary disease was significantly affected by northwest dryness syndrome. (3) the disease degree of skin dryness syndrome of lung Wei Kong orifices and deficiency of liver and kidney essence and blood in chronic obstructive lung group was significantly higher than that in control group. It was found that the skin dryness syndrome of lung Wei Kong orifices was the main characteristic of northwest dryness syndrome in Han patients with chronic obstructive lung disease, while the spleen and stomach dampness syndrome was the main characteristic of Uygur patients with chronic obstructive lung disease. The main syndromes of female northwest dryness syndrome were deficiency of liver and kidney essence and blood. (4) deficiency of qi syndrome was the main syndrome of northwest dryness syndrome in chronic obstructive lung patients, followed by yin deficiency syndrome. The severity of Yin-deficiency syndrome and Qi-deficiency syndrome in Uygur is higher than that in Han nationality, and the severity of Yin-deficiency syndrome and Qi-deficiency syndrome in female patients are higher than that in male, and the severity of male yang deficiency syndrome is higher than that of female. Conclusion: in the patients with COPD, women are more affected by northwest dryness syndrome than men, the Han nationality is more likely to suffer from northwest dryness syndrome than the Uygur nationality, and the skin dryness syndrome of lung Wei Kong orifices is the main characteristic of northwest dryness syndrome in Han nationality. Spleen and stomach dampness syndrome is the main characteristic of Uygur patients. The main syndromes of female patients are deficiency of liver and kidney essence and blood. The syndrome of skin dryness of lung Wei Kong orifices and deficiency of liver and kidney essence and blood are most closely related to the TCM syndromes of stable period of COPD in Kashi region of Xinjiang. Among the patients with chronic obstructive pulmonary disease, deficiency syndrome of qi was more common in northwest dryness syndrome, followed by yin deficiency syndrome; qi deficiency and yin deficiency syndrome were more serious in Uygur nationality than in Han nationality; deficiency syndrome of female patients was mainly manifested by qi deficiency syndrome and yin deficiency syndrome. Male with yang deficiency as the main syndromes.
【學位授予單位】:新疆醫(yī)科大學
【學位級別】:碩士
【學位授予年份】:2017
【分類號】:R259

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