本文選題：電針 + 面神經(jīng)損傷��； 參考：《針刺研究》2017年05期

【摘要】：目的:對(duì)比電針與手針對(duì)面神經(jīng)損傷兔面神經(jīng)雪旺細(xì)胞、髓鞘及線粒體等結(jié)構(gòu)形態(tài)學(xué)影響,探索電針治療面神經(jīng)損傷的機(jī)制。方法:新西蘭兔隨機(jī)分為正常組、假手術(shù)組、模型組、手針組、電針組,每組10只。經(jīng)面神經(jīng)壓榨復(fù)制面神經(jīng)損傷模型。電針組取"地倉(cāng)""下關(guān)""太陽(yáng)""陽(yáng)白"進(jìn)行電針治療,每次30min;手針組選穴同電針組,每10min平補(bǔ)平瀉捻轉(zhuǎn)手法行針1次,留針30min。兩組均每日治療1次,共治療28d。每7d進(jìn)行1次面肌運(yùn)動(dòng)評(píng)分,28d后電鏡觀察各組面神經(jīng)超微結(jié)構(gòu)。結(jié)果:治療后,假手術(shù)組與正常組比較各項(xiàng)結(jié)果未見(jiàn)明顯變化(P0.05)。模型組在面肌運(yùn)動(dòng)評(píng)分、超微結(jié)構(gòu)形態(tài)學(xué)變化以及單位面積軸突數(shù)目、髓鞘厚度、軸突面積等方面均差于正常組(P0.05);兩治療組面肌運(yùn)動(dòng)評(píng)分、超微結(jié)構(gòu)形態(tài)學(xué)變化以及單位面積軸突數(shù)目、髓鞘厚度、軸突面積均好于模型組(P0.05);電針組各項(xiàng)結(jié)果均好于手針組(P0.05)。結(jié)論:在面神經(jīng)損傷的治療中,電針比手針更能促進(jìn)軸漿線粒體增殖、髓鞘恢復(fù)以及軸索再生,這可能是電針治療面神經(jīng)損傷效果優(yōu)于手針的機(jī)制之一。
[Abstract]:Aim: to compare the morphological effects of electroacupuncture on Schwann cells, myelin sheath and mitochondria of facial nerve in rabbits with facial nerve injury, and to explore the mechanism of electroacupuncture in the treatment of facial nerve injury. Methods: new Zealand rabbits were randomly divided into normal group, sham operation group, model group, hand acupuncture group and electroacupuncture group. Facial nerve injury model was established by facial nerve compression. In the electroacupuncture group, the acupuncture group was treated with electroacupuncture for 30 mins each time, and the acupoints of the hand acupuncture group were selected with the same electroacupuncture group, and the acupuncture was performed once per 10min, and the needle was kept for 30 mins. The acupuncture group was treated with "Dicuang", "Xiaguan" and "Yangbai" for 30 minutes. The two groups were treated once a day for 28 days. Facial nerve ultrastructure was observed by electron microscope every 7 days. Results: after treatment, the sham-operation group and the normal group showed no significant changes in the results (P0.05). The average value of facial muscle motor score, ultrastructural morphology, number of axons per unit area, myelin sheath thickness and axon area in the model group were lower than those in the normal group (P0.05). The morphological changes of ultrastructure, the number of axons per unit area, the thickness of myelin sheath and the area of axons in the model group were better than those in the model group (P0.05), and the results of electroacupuncture group were better than those of the hand acupuncture group (P0.05). Conclusion: in the treatment of facial nerve injury, electroacupuncture can promote mitochondria proliferation, myelin sheath recovery and axonal regeneration more than hand acupuncture, which may be one of the mechanisms of electroacupuncture in treating facial nerve injury better than hand acupuncture.
【作者單位】： 青島市海慈醫(yī)療集團(tuán);山東中醫(yī)藥大學(xué)針灸推拿學(xué)院;
【基金】：國(guó)家自然科學(xué)基金項(xiàng)目(No.81273917)
【分類(lèi)號(hào)】：R245

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