本文選題：土茯苓 + 濕熱蘊(yùn)結(jié)��； 參考：《廣州中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的:古代醫(yī)家辯證用藥的經(jīng)驗(yàn)中,含有土茯苓的復(fù)方中藥湯劑的治療效果確切,為針對(duì)濕熱蘊(yùn)結(jié)型急性期痛風(fēng)性關(guān)節(jié)炎的患者,給予土茯苓單味湯劑口服,觀察對(duì)比治療前后患者的VAS評(píng)分、白細(xì)胞計(jì)數(shù)、血沉、C反應(yīng)蛋白、血尿酸實(shí)驗(yàn)室檢驗(yàn)指標(biāo)的波動(dòng)情況,為進(jìn)一步肯定土茯苓單味湯劑的療效提供更有力的證據(jù)。方法:挑選來自廣州中醫(yī)藥大學(xué)附屬骨傷科醫(yī)院,自2016年2月至2017年2月期間,符合該研究的80例患有濕熱蘊(yùn)結(jié)型急性期痛風(fēng)性關(guān)節(jié)炎的患者,經(jīng)過隨機(jī)化配平,均分為治療組40例及對(duì)照組40例,于治療前測(cè)定其VAS評(píng)分、白細(xì)胞計(jì)數(shù)、血沉、C反應(yīng)蛋白、血尿酸,治療組采用土茯苓單味治療,選廣東產(chǎn)土茯苓100g,加水500ml,煎取200ml,1劑/日,分早晚兩次飯后溫服,聯(lián)合依托考昔片口服60mg/次,1次/d;對(duì)照組單純給予依托考昔片口服60mg/次,1次/d。1周為1療程,共治療2周。分別在1周后、2周后,兩組患者復(fù)診分別時(shí)測(cè)定VAS評(píng)分、白細(xì)胞、血沉、C反應(yīng)蛋白、血尿酸。比較分析組間及治療前后各個(gè)指標(biāo)波動(dòng)情況。結(jié)果:1.兩組患者在治療前VAS評(píng)分、白細(xì)胞、血沉、C反應(yīng)蛋白、血尿酸無明顯差異,差異無統(tǒng)計(jì)學(xué)意義(P0.05),組間有可比性。2.治療組及對(duì)照組的患者經(jīng)治療后的VAS評(píng)分、白細(xì)胞、血沉、C反應(yīng)蛋白、血尿酸指標(biāo)較治療前顯著下降,有明顯差異(P0.05)。治療組各指標(biāo)較對(duì)照組下降明顯,尤其是血尿酸,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:濕熱蘊(yùn)結(jié)型急性期痛風(fēng)性關(guān)節(jié)炎患者經(jīng)土茯苓單味湯劑聯(lián)合依托考昔片治療后,較單純依托考昔片治療具有更好的療效,并且能進(jìn)一步降低白細(xì)胞、血沉、C反應(yīng)蛋白,尤其是血尿酸。
[Abstract]:Objective: in the experience of dialectical medicine of ancient physicians, the curative effect of compound traditional Chinese medicine decoction containing Tupia cocos is definite. In order to treat the patients with acute gouty arthritis of dampness and heat accumulation type in acute stage, Tuckaoling decoction is given orally. The fluctuation of VAS score, white blood cell count, erythrocyte sedimentation rate C reactive protein and blood uric acid laboratory test were observed and compared before and after treatment. Methods: from February 2016 to February 2017, 80 patients with acute gouty arthritis of damp-heat accumulation type were selected from the affiliated Orthopedic and Trauma Hospital of Guangzhou University of traditional Chinese Medicine. All patients were divided into treatment group (n = 40) and control group (n = 40). Their VAS score, white blood cell count, erythrocyte sedimentation rate C reactive protein, blood uric acid were measured before treatment. The patients in the control group were treated with etacoxib orally for 1 / d / d for 1 / 2 / d respectively, while the control group were given etacoxib orally for 1 / d / 1 / d ~ (1) week for a course of treatment for 2 weeks. After 1 week and 2 weeks, the VAS score, white blood cell, erythrocyte sedimentation rate C reactive protein and uric acid were measured. To compare and analyze the fluctuation of each index between groups and before and after treatment. The result is 1: 1. There was no significant difference in VAS score, leukocyte, erythrocyte sedimentation rate C reactive protein and serum uric acid between the two groups before treatment, but there was no significant difference between the two groups (P 0.05). The VAS score, WBC, ESR C reactive protein and serum uric acid index of the patients in the treatment group and the control group were significantly lower than those before treatment (P 0.05). The indexes of the treatment group were significantly lower than that of the control group, especially the serum uric acid, the difference was statistically significant (P 0.05). Conclusion: the patients with acute gouty arthritis of dampness and heat accumulation type can get better curative effect after treatment with TuPoria Ling single decoction combined with relying on Coxie tablet, and can further reduce white blood cell, erythrocyte sedimentation rate and C-reactive protein, compared with only relying on Coxie tablet, and can further reduce WBC, erythrocyte sedimentation rate and C-reactive protein. Especially blood uric acid.
【學(xué)位授予單位】：廣州中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R259
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本文編號(hào)：1938875