本文選題：橋本甲狀腺炎 + 亞臨床期��； 參考：《遼寧中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：橋本甲狀腺炎(Hashimoto thyroiditis,HT),又叫慢性淋巴細(xì)胞性甲狀腺炎(Chronic Lymphocytic Thyroiditis,CLT),是一種臨床上常見的器官特異性自身免疫疾病,是自身免疫性甲狀腺疾病(Auto Immuno Thyroiditis Disease,AITD)的一個(gè)類型。其主要特點(diǎn)是特異性甲狀腺自身抗體甲狀腺球蛋白抗體(TGAb)、甲狀腺過氧化物酶抗體(TPOAb)的增高和甲狀腺內(nèi)淋巴細(xì)胞浸潤,最終導(dǎo)致甲狀腺組織結(jié)構(gòu)被破壞,造成甲狀腺功能低下。現(xiàn)代醫(yī)學(xué)認(rèn)為其病因主要包括遺傳因素、自身免疫因素、環(huán)境因素。在治療上多根據(jù)甲功水平對(duì)甲亢或甲減進(jìn)行相應(yīng)治療,但對(duì)于縮小甲狀腺及抑制自身免疫反應(yīng),降低抗體水平仍缺乏理想的方法。傳統(tǒng)醫(yī)學(xué)認(rèn)為橋本病的發(fā)生主要是情志因素、環(huán)境因素及體質(zhì)因素導(dǎo)致機(jī)體臟腑功能失調(diào),痰凝、氣滯、血瘀等病理產(chǎn)物搏結(jié)于頸前而發(fā)病。導(dǎo)師從事內(nèi)分泌臨床工作多年,臨床上運(yùn)用中醫(yī)特色辨證論治,對(duì)橋本病分期治療,針對(duì)亞臨床甲功異常,并伴有兩項(xiàng)抗體顯著升高的亞臨床期治療療效顯著。導(dǎo)師認(rèn)為亞臨床期為疾病初期,情緒因素是此期發(fā)生的關(guān)鍵,肝失疏泄,肝郁克脾,脾氣虧虛,輸津失常,凝聚成痰,痰隨氣行,無處不到,停于頸前,則見頸前腫大。亞臨床甲亢期以肝郁脾虛為重,亞臨床甲減期則以脾腎氣虛為主。導(dǎo)師分期治療橋本病亞臨床期,以疏肝理氣為基礎(chǔ),佐以健脾補(bǔ)腎,并將中醫(yī)臟腑與現(xiàn)代醫(yī)學(xué)中免疫功能聯(lián)系起來,治病同時(shí)重視與患者情感上的交流與溝通,收效顯著。
[Abstract]:Hashimoto thyroiditis, or chronic lymphocytic thyroiditis, is a common organ specific autoimmune disease and a type of autoimmune thyroid disease. Its main characteristics are the increase of specific thyroid autoantibody thyroglobulin antibody (TGAbA) and thyroid peroxidase antibody (TPOAbb) and the infiltration of intrathyroid lymphocytes resulting in the destruction of thyroid tissue structure and the hypothyroidism. Modern medicine thinks its etiology mainly includes heredity factor, autoimmune factor, environment factor. Hyperthyroidism or hypothyroidism were treated according to the level of thyroid work, but there was still no ideal method for reducing thyroid gland, inhibiting autoimmune reaction and reducing antibody level. Traditional medicine believes that Hashimoto's disease is mainly caused by emotional factors, environmental factors and physical factors leading to dysfunction of viscera function, phlegm coagulation, qi stagnation, blood stasis and other pathological products in front of the neck. The tutor engaged in the endocrine clinical work for many years, the clinical use Chinese medicine characteristic differentiation treatment, to Hashimoto disease stage treatment, aimed at the subclinical thyroid dysfunction, and accompanied by two significantly increased antibody subclinical treatment effect is remarkable. The tutor thinks that the subclinical stage is the initial stage of the disease, the emotional factor is the key to the occurrence of this period, the liver is lost, the liver is depressed, the spleen is deficient, the transfusion of Tianjin is abnormal, the sputum is condensed into phlegm, the phlegm follows the Qi, nowhere is less than, stop in the front of the neck, see the neck before swelling. In the subclinical hyperthyroidism stage, liver stagnation and spleen deficiency were the most important, while the subclinical hypothyroidism was mainly spleen and kidney qi deficiency. The teacher treated Hashimoto's disease by stages in subclinical stage, based on soothing liver and regulating qi, adding spleen and tonifying kidney, connecting the viscera of traditional Chinese medicine with immunological function in modern medicine, paying attention to the communication and communication with patients' emotion, and achieving remarkable results.
【學(xué)位授予單位】：遼寧中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R259

【參考文獻(xiàn)】

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