吳氏扶陽(yáng)流派學(xué)術(shù)思想診治鼻鼽的理論探討與臨床應(yīng)用研究
本文關(guān)鍵詞: 吳氏扶陽(yáng)流派學(xué)術(shù)思想 鼻鼽 陽(yáng)虛型 扶陽(yáng)方 變應(yīng)性鼻炎 出處:《云南中醫(yī)學(xué)院》2017年碩士論文 論文類型:學(xué)位論文
【摘要】:目的:1.歸納整理吳氏扶陽(yáng)流派診治鼻鼽(變應(yīng)性鼻炎)的學(xué)術(shù)思想,總結(jié)吳氏扶陽(yáng)流派診治鼻鼽(變應(yīng)性鼻炎)的理、法、方藥。2.運(yùn)用總結(jié)的吳氏扶陽(yáng)流派扶陽(yáng)方治療陽(yáng)虛型鼻鼽(變應(yīng)性鼻炎)患者,觀察其臨床療效,為臨床推廣應(yīng)用提供有力證據(jù)。方法:1.理論研究方法通過(guò)文獻(xiàn)檢索及手工查尋等方法收集吳氏扶陽(yáng)流派相關(guān)文獻(xiàn)、著作,篩選吳氏扶陽(yáng)流派學(xué)術(shù)思想診治鼻鼽(變應(yīng)性鼻炎)的相關(guān)文獻(xiàn)?偨Y(jié)、提煉吳氏扶陽(yáng)流派學(xué)術(shù)思想診治鼻鼽(變應(yīng)性鼻炎)的相關(guān)理論。2.臨床研究方法收集60例陽(yáng)虛型鼻鼽(變應(yīng)性鼻炎)患者,按照隨機(jī)分組法將病人隨機(jī)分為治療組和對(duì)照組。每組各30例。治療組予扶陽(yáng)方治療,對(duì)照組予中成藥《金匱腎氣丸》治療,療程為兩周。治療后,對(duì)治療前后的嗜酸粒細(xì)胞及癥狀體征評(píng)分運(yùn)用統(tǒng)計(jì)學(xué)的方法評(píng)估療效。結(jié)果:1.理論研究結(jié)果:通過(guò)大量數(shù)據(jù)資料和文獻(xiàn)醫(yī)案的研究,歸納整理吳氏扶陽(yáng)流派診治鼻鼽(變應(yīng)性鼻炎)的學(xué)術(shù)思想,同時(shí)請(qǐng)教了吳氏扶陽(yáng)流派傳承人吳生元先生的意見,最終由導(dǎo)師周家璇教授確定治療陽(yáng)虛型鼻鼽(變應(yīng)性鼻炎)的理、法、方藥。2.臨床研究結(jié)果2.1實(shí)驗(yàn)的60例研究對(duì)象,在性別、年齡、癥狀、體征等方面,比較無(wú)統(tǒng)計(jì)學(xué)差異,具有可比性。到治療結(jié)束時(shí)脫落3例,剩余57例結(jié)果有效。其中治療組29例,對(duì)照組28例。2.2治療結(jié)束后,對(duì)57例有效樣本進(jìn)行統(tǒng)計(jì)分析:對(duì)照組總有效率:67.86%;治療組總有效率:89.66%。對(duì)照組和治療組治療后癥狀體征總積分比較:t=-2.869,P=0.006,P0.01。兩組比較差異性顯著,有統(tǒng)計(jì)學(xué)意義。治療組在改善打噴嚏、流清涕、鼻塞、鼻癢、乏力癥狀方面有極顯著性差異,效果顯著;在改善畏寒、自汗方面,有顯著性差異;對(duì)照組在改善打噴嚏,流清涕、鼻塞、鼻癢、自汗等癥狀方面有極顯著性差異,效果顯著;在改善畏寒、乏力癥狀方面,無(wú)顯著性差異。兩組患者在改善鼻黏膜蒼白、水腫方面,均有顯著差異。在減少患者的鼻腔分泌物中嗜酸性粒細(xì)胞上,兩組均有統(tǒng)計(jì)學(xué)意義,且治療組較對(duì)照組效果更佳。2.3治療前后的統(tǒng)計(jì)學(xué)評(píng)分比較,兩組通過(guò)治療后病情均有不同程度減輕,且治療組優(yōu)于對(duì)照組。結(jié)論:1.在本次實(shí)驗(yàn)中,吳氏扶陽(yáng)學(xué)術(shù)思想可用于治療陽(yáng)虛型鼻鼽(變應(yīng)性鼻炎)患者,在臨床可以探索推廣應(yīng)用。2.總結(jié)的扶陽(yáng)方通過(guò)臨床研究發(fā)現(xiàn)治療陽(yáng)虛型鼻鼽(變應(yīng)性鼻炎)有效,可以很好改善陽(yáng)虛型鼻鼽(變應(yīng)性鼻炎)患者鼻塞、流涕、噴嚏、畏寒、出汗、鼻癢、乏力及鼻黏膜腫脹等癥狀和體征,對(duì)患者鼻涕中嗜酸性粒細(xì)胞有一定的調(diào)節(jié)作用。3.臨床安全性觀察:在整個(gè)療程中,治療組與對(duì)照組均未發(fā)現(xiàn)不良反應(yīng)病例。
[Abstract]:Objective\\\? Prescription medicine .2.Use the summarized Wu's Fu Yang school to treat the patients with allergic rhinitis with Yang deficiency type, and observe its clinical curative effect. To provide strong evidence for clinical popularization and application. Methods: 1. Theoretical research methods collect relevant literature and works of Wu's Fu Yang school through literature retrieval and manual search. To screen the literature on the diagnosis and treatment of allergic rhinitis by Wu Fuyang school. Abstract the relevant theories of Wu's Fu Yang School for the diagnosis and treatment of allergic rhinitis. 2. Clinical study methods collected 60 cases of allergic rhinitis with Yang deficiency type. The patients were randomly divided into treatment group (n = 30) and control group (n = 30). The treatment group was treated with Fuyang prescription, while the control group was treated with traditional Chinese patent medicine (Jinkui Shenqi pills) for two weeks. The score of eosinophils and symptoms and signs before and after treatment was evaluated by statistical method. Results: 1. Theoretical study results: through a large number of data and medical documents, Summing up and sorting out the academic thoughts of Wu's Fu Yang school in the diagnosis and treatment of allergic rhinitis, and consulting the inheritor of Wu's Fu Yang school, Mr. Wu Shengyuan, Finally, Professor Zhou Jiaxuan, his mentor, determined the principles, methods, prescriptions and medicines for the treatment of allergic rhinitis of Yang deficiency type. There was no statistical difference in the sex, age, symptoms, signs and so on among the 60 experimental subjects in the clinical study results 2.1. By the end of the treatment, 3 cases had dropped out, the remaining 57 cases were effective. 29 cases in the treatment group and 28 cases in the control group. Statistical analysis of 57 effective samples: the total effective rate of the control group was: 67.866.The total effective rate of the treatment group was: 89.66.The total score of symptoms and signs after treatment in the control group and the treatment group was higher than that in the control group and the treatment group. The difference between the two groups was significant, and there was statistical significance between the two groups. There were significant differences in the symptoms of runny, nasal obstruction, itching and fatigue, significant difference in improving chills and sweating, and in the control group in improving sneezing, runny, stuffy, and itchy nose. There was significant difference in symptoms such as self-sweating, and there was no significant difference between the two groups in improving symptoms of chills and fatigue. In reducing eosinophils in nasal secretion of patients, there was statistical significance between the two groups, and the effect of treatment group was better than that of control group before and after treatment, and the score of eosinophils in the treatment group was better than that in the control group before and after treatment. The treatment group was superior to the control group. Conclusion 1. In this experiment, Wu Fuyang's academic thought can be used to treat the allergic rhinitis of Yang deficiency type. (2) in clinical practice, we can explore and popularize the application of Fuyang prescription. Through clinical studies, we find that Fuyang prescription is effective in treating allergic rhinitis with Yang deficiency type, and can improve nasal congestion, runny discharge, sneeze, and chills in patients with allergic rhinitis with Yang deficiency type. Sweating, itching, fatigue, swelling of nasal mucosa and other symptoms and signs, the eosinophils in nasal snot can be regulated to a certain extent .3.Clinical safety observation: in the whole course of treatment, no adverse reactions were found in the treatment group and the control group.
【學(xué)位授予單位】:云南中醫(yī)學(xué)院
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類號(hào)】:R276.1
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