大黃明礬湯肛內(nèi)滴注防治痔病術(shù)后出血的臨床研究
本文關(guān)鍵詞: 痔病術(shù)后 大黃明礬湯 止血 云南紅藥膠囊 臨床觀察 出處:《云南中醫(yī)學(xué)院》2017年碩士論文 論文類型:學(xué)位論文
【摘要】:目的:觀察大黃明礬湯肛內(nèi)滴注防治痔病(濕熱下注型)術(shù)后出血患者的臨床療效。方法:選取2015年12月-2016年12月昆明市中醫(yī)醫(yī)院肛腸科72例混合痔術(shù)后患者,將其隨機(jī)分為治療組和對(duì)照組,扣除脫落病例10例,最終有效病例62例,其中治療組為32例,對(duì)照組30例,均予以混合痔外剝內(nèi)扎術(shù)治療,術(shù)后第1天開始用藥,治療組使用大黃明礬湯肛內(nèi)滴注,每次100ml,每日早、晚各一次,同時(shí)口服云南紅藥膠囊,每次兩粒(規(guī)格0.25),每天三次,療程七天;對(duì)照組口服云南紅藥膠囊,每次兩粒(規(guī)格0.25),每天三次,療程七天。術(shù)后第3天觀察記錄患者便時(shí)出血情況。結(jié)果:1.在觀察過程中的72例患者,其中有5例因個(gè)人原因或失訪退出觀察,5例患者未按要求服藥不計(jì)入統(tǒng)計(jì)。最終有效病例數(shù)62例(治療組為32例,對(duì)照組30例)。治療組和對(duì)照組病例在性別、年齡、病程、手術(shù)前病情、治療前便時(shí)出血積分情況等方面無顯著性差異(P0.05),在統(tǒng)計(jì)學(xué)上具有可比性。2.術(shù)后第3天、第7天觀察兩組排便時(shí)的出血情況,術(shù)后第3天治療組排便時(shí)出血積分少于對(duì)照組便時(shí)出血積分,兩組間比較差異顯著有統(tǒng)計(jì)學(xué)意(P0.05),術(shù)后第7天治療組便時(shí)出血積分少于對(duì)照組兩組比較差異顯著有統(tǒng)計(jì)學(xué)意義(P0.05);術(shù)后第7天治療組顯效率和有效率分別為78.12%、96.75%,對(duì)照組分別為40%、73.33%,兩組顯效率、總有效率比較治療組均高于對(duì)照組,差異顯著有統(tǒng)計(jì)學(xué)意義(P=0.0010.05)。3.安全性判定:兩組治療期間均無嚴(yán)重不良反應(yīng),呼吸、血壓、體溫、脈搏等主要生命體征未觀察到異常波動(dòng)。結(jié)論:大黃明礬湯具有收斂止血、化瘀止血之功,肛內(nèi)滴注同時(shí)口服云南紅藥膠囊能明顯改善痔病術(shù)后排便時(shí)出血癥狀,其中治療組顯效率和有效率分別為78.12%、96.75%,對(duì)照組分別為40%、73.33%(P㩳0.05)。臨床研究表明大黃明礬湯肛內(nèi)滴注同時(shí)口服云南紅藥膠囊能減少術(shù)后排便時(shí)出血癥狀,提高患者的生活質(zhì)量。其臨床療效優(yōu)于單純口服云南紅藥膠囊,且不良反應(yīng)更少,療效明確,值得臨床推廣應(yīng)用。
[Abstract]:Objective: To observe the effect of Rhubarb Decoction in prevention and treatment of rectal drip alum hemorrhoids (heat bet type) the clinical curative effect of patients with postoperative bleeding. Methods: December 2015 -2016 December 2009 in Kunming Hospital of Traditional Chinese Medicine in 72 cases of Anorectal Postoperative mixed hemorrhoids patients, which were randomly divided into treatment group and control group, 10 cases of loss deduction, the final effective in 62 cases, the treatment group of 32 cases, 30 cases in the control group were treated with mixed hemorrhoids Milligan surgery, medication began first days after the operation, the treatment group used Rhubarb decoction alum anus drip, each time 100ml, daily early, late each time, and oral administration of Yunnan Hongyao capsule, two pills (size 0.25), three times a day, a course of seven days; the control group oral administration of Yunnan Hongyao capsule, 2 capsules (size 0.25), three times a day, a course of seven days. They were recorded when bleeding was observed third days after operation. Results: 1. in the observation of 72 patients, including 5 cases for a One reason or lost from the observation, 5 cases of patients with no medication is not included in the statistics. According to the requirements of the final effective 62 cases (treatment group 32 cases, control group 30 cases). The treatment group and the control groups were gender, age, disease duration, disease before surgery, there was no significant difference before treatment was bleeding integral aspects (P0.05), was comparable to.2. after third days, seventh days of bleeding were observed in two groups during defecation, after third days of treatment group defecation hemorrhage hemorrhage control group was less than the integral integral, the difference between the two groups was statistically significant (P0.05) operation, Italy after seventh days of treatment group had bleeding less points than the differences were compared between the two groups was statistically significant (P0.05); after seventh days of treatment group of significant efficiency and efficiency were 78.12%, 96.75%, the control group were 40%, 73.33%, two group of significant efficiency, the total effective rate of the treatment group were higher than those of the control Group, there were significant differences (P=0.0010.05) to determine the safety of.3.: during the two groups had no serious adverse reactions, breathing, blood pressure, body temperature, pulse and other vital signs were not observed abnormal fluctuations. Conclusion: Rhubarb decoction has styptic alum, removing blood stasis hemostatic function, anus drip and oral administration of Yunnan Hongyao capsule can significantly improve symptoms of bleeding hemorrhoids postoperative defecation, the treatment group significant efficiency and efficiency were 78.12%, 96.75%, the control group were 40% and 73.33% (P? 0.05). Clinical studies show that rhubarb decoction in anus drip alum and oral administration of Yunnan Hongyao capsule can reduce postoperative bleeding during defecation. To improve the quality of life of patients. Its clinical curative effect is better than oral administration of Yunnan Hongyao capsule, and less adverse reactions, the effect is clear, it is worthy of clinical application.
【學(xué)位授予單位】:云南中醫(yī)學(xué)院
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類號(hào)】:R266
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