本文關(guān)鍵詞： 益氣養(yǎng)陰行氣潤腸法 中藥顆粒劑 老年人 功能性便秘 臨床療效評價　出處：《河北醫(yī)科大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:在中醫(yī)理論的指導(dǎo)下,運用益氣養(yǎng)陰行氣潤腸法治療老年人功能性便秘,科學(xué)系統(tǒng)地對受試者療效進行評分、記錄、數(shù)據(jù)分析,對此方法的臨床療效進行評價。方法:本研究采取隨機、對照的方法,將2015年9月至2016年11月間,河北省中醫(yī)院肛腸二科門診就診的老年功能性便秘患者中屬于中醫(yī)診斷為氣陰虧虛證型的病歷,共60例,分為治療組和對照組,每組30例。治療組予益氣養(yǎng)陰行氣潤腸功效的中藥顆粒劑口服,對照組予麻仁軟膠囊口服,兩組均以10天為1療程,共治療和觀察記錄3個療程,將兩組患者治療前后的臨床癥狀,按評分標準打分。治療結(jié)束4周后對兩組患者進行隨訪,按評分標準打分。對兩組最終收集的數(shù)據(jù),使用SPSS19.0統(tǒng)計軟件進行統(tǒng)計學(xué)分析,從多角度評價本方法的臨床療效。治療期間,囑全部患者停止使用影響腸動力的藥物,合理膳食,規(guī)律作息,積極配合。結(jié)果:共完成臨床觀察病例52例,包括治療組27例,對照組25例。1治療組與對照組綜合療效比較,總有效率治療組為85.2%,對照組為72.0%,兩組總有效率比較P0.05,無統(tǒng)計學(xué)意義,說明兩組治療方法均有效;總顯效率治療組33.3%,對照組8.0%,P0.05,說明有統(tǒng)計學(xué)意義,治療組療效優(yōu)于對照組;2性別與療效的相關(guān)性比較,男性患者兩種治療的療效無差異,女性患者兩種治療的療效無差異。治療組男性與女性患者療效無差異,對照組男性與女性患者療效無差異;3病程與療效的相關(guān)性比較,病程在5年內(nèi)及10年以上的患者中治療組療效優(yōu)于對照組;4兩組受試者3個療程治療結(jié)束,4周后隨訪,治療組復(fù)發(fā)率為17.4%,對照組復(fù)發(fā)率為50%,兩組復(fù)發(fā)率經(jīng)卡方檢驗:χ2=4.96,P=0.03,P0.05,有統(tǒng)計學(xué)差異,說明遠期療效治療組優(yōu)于對照組。結(jié)論:益氣養(yǎng)陰行氣潤腸法對老年人功能性便秘的療效確切,在綜合療效、較長病程的老年人功能性便秘的治療方面效果顯著,且復(fù)發(fā)率低,無明顯副作用,值得推廣。
[Abstract]:Objective: under the guidance of traditional Chinese medicine theory, the treatment of functional constipation in the elderly with the method of nourishing qi and nourishing yin and nourishing qi and nourishing intestines was used to scientifically and systematically evaluate, record and analyze the curative effect of the subjects. Methods: a randomized, controlled method was used to evaluate the clinical efficacy of this method from September 2015 to November 2016. Among the elderly patients with functional constipation diagnosed as deficiency of qi and yin, 60 cases were divided into treatment group and control group. 30 cases in each group. The treatment group was treated with traditional Chinese medicine granules of invigorating qi, nourishing yin and nourishing qi and nourishing intestines. The control group was given Maren soft capsule orally. The two groups were treated with 10 days as a course of treatment, and three courses of treatment were observed and recorded. The clinical symptoms of the two groups before and after treatment were scored according to the scoring standard. The patients in the two groups were followed up 4 weeks after the treatment and scored according to the scoring standard. The final data collected in the two groups were statistically analyzed by SPSS19.0 statistical software. The clinical effect of this method was evaluated from various angles. During the treatment, all patients were told to stop using drugs affecting intestinal motility, reasonable diet, regular rest and active cooperation. Results: a total of 52 cases of clinical observation were completed, including 27 cases in the treatment group. The total effective rate was 85.2in the treatment group and 72.0 in the control group. There was no statistical significance in the total effective rate between the two groups (P 0.05), which indicated that the two treatment methods were effective. The total effective rate of treatment group was 33. 3 and that of control group was 8. 0% P 0. 05, which indicated that there was statistical significance. The curative effect of treatment group was better than that of control group. There was no difference in curative effect between male and female patients in treatment group, and there was no difference between male and female patients in control group. The curative effect of the treatment group was better than that of the control group in the course of 5 years or more than 10 years. The patients in the two groups were followed up for 4 weeks after 3 courses of treatment. The recurrence rate of the treatment group was 17.4 and that of the control group was 50. The recurrence rate of the two groups was tested by chi-square test. There was statistical difference between the two groups, indicating that the long-term curative effect of the treatment group was better than that of the control group. Conclusion: the therapy of nourishing qi, nourishing yin and nourishing qi and nourishing the intestines is effective in treating functional constipation in the elderly. In the treatment of functional constipation in the elderly with long course of disease, the curative effect is significant, and the recurrence rate is low, no obvious side effects, so it is worth popularizing.
【學(xué)位授予單位】：河北醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R256.35

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