本文關(guān)鍵詞：潰瘍性結(jié)腸炎的證型分布規(guī)律及其相關(guān)因素研究　出處：《南京中醫(yī)藥大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

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【摘要】：目的:研究潰瘍性結(jié)腸炎(UC)的中醫(yī)證型分布規(guī)律及其相關(guān)因素的關(guān)系,為臨床診治提供依據(jù)。方法:收集2015.11-2017.03江蘇省中醫(yī)院診治的潰瘍性結(jié)腸炎患者的臨床資料,總結(jié)UC中醫(yī)證型分布規(guī)律及其相關(guān)因素的關(guān)系。結(jié)果:共收集300例病例,其中男性167例,女性133例,男女比例為1.26:1,年齡最小14歲,最大76歲,平均年齡為41.65± 13.35歲,中位年齡41歲。病史為1-29年。緩解期77例(占25.67%),活動(dòng)期223例(占74.33%)�；顒�(dòng)期臨床類型初發(fā)型14例(占6.29%),復(fù)發(fā)型209例(占93.72%);活動(dòng)期內(nèi)嚴(yán)重程度輕度126例(占56.50%)、中度55例(占24.66%)、重度42例(占18.83%);病變范圍直腸型(E1)72例(占32.29%),左半結(jié)腸型(E2)82例(占36.77%),廣泛結(jié)腸型(E3)69例(占30.94%)。經(jīng)統(tǒng)計(jì),中醫(yī)辨證可分為六型,即脾虛濕熱證140例(占46.67%),大腸濕熱證90例(占30.00%),肝郁脾虛證37例(占12.33%),脾腎陽(yáng)虛證22例(占7.33%),陰血虧虛證7例(占2.33%),寒熱錯(cuò)雜證4例(占1.33%)。腸鏡下表現(xiàn)與中醫(yī)證型有一定的相關(guān)性,UC緩解期以脾虛濕熱證多見(jiàn),活動(dòng)期以大腸濕熱、脾虛濕熱證多見(jiàn);UC活動(dòng)期大腸濕熱證癥狀較重,腸粘膜病變程度比較嚴(yán)重,見(jiàn)于中、重度;而脾虛濕熱證、肝郁脾虛證、脾腎陽(yáng)虛證癥狀相對(duì)較輕,腸粘膜病變程度較輕,見(jiàn)于輕度;UC活動(dòng)期大腸濕熱證癥狀較重,腸粘膜病變范圍以E3為主;而脾虛濕熱證癥狀相對(duì)較輕,腸粘膜病變范圍相對(duì)較局部,以E1、E2為主。結(jié)論:臨床上緩解期以脾虛濕熱證為主,活動(dòng)期以大腸濕熱、脾虛濕熱證為主,活動(dòng)期證型分布與嚴(yán)重程度、病變范圍有關(guān)。
[Abstract]:Objective: To study the distribution of TCM syndrome types of ulcerative colitis (UC) and its related factors, and to provide a basis for clinical diagnosis and treatment. Methods: the clinical data of patients with ulcerative colitis diagnosed by 2015.11-2017.03 Jiangsu Province Traditional Chinese Medicine Hospital were collected, and the relationship between UC TCM Syndrome Distribution and related factors was summarized. Results: a total of 300 cases were collected, including 167 males and 133 females. The male to female ratio is 1.26:1, the youngest is 14 years old, the largest is 76 years old, the average age is 41.65 + 13.35 years old, and the median age is 41 years old. The history of the disease was 1-29 years. The remission period was 77 cases (25.67%), and the active period was 223 cases (74.33%). Active clinical onset type 14 cases (6.29%), recurrent in 209 cases (93.72%); activities during the period of the severity of mild in 126 cases (56.50%), 55 (24.66%) cases of moderate and severe in 42 cases (18.83%); the lesion of rectal type (E1) 72 cases (32.29%) that left colon type (E2) and 82 cases (36.77%), wide type (E3) of 69 cases of colon (30.94%). According to statistics, TCM can be divided into six types, namely, spleen deficiency and dampness heat syndrome in 140 cases (46.67%), damp heat syndrome in 90 cases (30%), 37 cases of liver stagnation and spleen deficiency syndrome (12.33%), Yang deficiency of spleen and kidney in 22 cases (7.33%), Yin and blood deficiency in 7 cases (2.33%), 4 cold and heat syndrome (1.33% cases). Endoscopic manifestations and syndromes have some relevance, UC remission in spleen deficiency and dampness heat syndrome, active in the large intestine damp heat, spleen deficiency and dampness heat syndrome more active UC; damp heat syndrome of severe symptoms, the severity of intestinal mucosal lesions is more serious, in moderate and severe; and heat dampness, spleen deficiency and liver stagnation and spleen deficiency card, spleen and kidney yang deficiency syndrome is relatively light, the degree of intestinal mucosal lesion was found in the light, mild; active UC damp heat syndrome of severe symptoms, intestinal mucosal lesions in the E3; and the spleen deficiency damp heat syndrome of relatively mild symptoms, intestinal mucosal lesions are relatively local, E1, E2. Conclusion: spleen deficiency and dampness heat syndrome are the main causes of remission in the clinical stage, mainly in the large intestine, dampness heat, spleen deficiency and dampness heat syndrome. The distribution of syndromes in active stage is related to the severity and the range of lesions.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R259

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