基于流體網(wǎng)絡(luò)的人體血液體循環(huán)分析
發(fā)布時(shí)間:2017-12-27 10:16
本文關(guān)鍵詞:基于流體網(wǎng)絡(luò)的人體血液體循環(huán)分析 出處:《中國生物醫(yī)學(xué)工程學(xué)報(bào)》2017年05期 論文類型:期刊論文
更多相關(guān)文章: 體循環(huán) 流體網(wǎng)絡(luò)模型 血流動力學(xué) 平均法
【摘要】:基于中醫(yī)脈診原理,研究人體各器官流阻變化對血流動力學(xué)參數(shù)的影響。建立人體血液體循環(huán)流體網(wǎng)絡(luò)模型,采用10次諧波血流動力學(xué)表達(dá)式模擬心臟輸出。改變各器官流阻,流阻比η分別取值0.5、1.0、1.5、2.0、2.5、3.0,利用平均法求解模型。假設(shè)心輸出量一定,結(jié)果表明:隨著流阻增大對應(yīng)分支流量下降;不同分支流阻增大均能使主動脈平均壓力上升,當(dāng)流阻比η=3.0時(shí),腦、肝、腎、胃、腸、脾分支流阻增大引起主動脈壓力較正常值分別增大23.29%、16.42%、14.67%、9.69%、9.59%、7.82%;肝和腎分支流阻變化對橈動脈影響較大,當(dāng)流阻比η=3.0時(shí),橈動脈壓力較正常值分別增大22.85%和11.17%,而其他器官分支流阻變化對橈動脈影響很小;對于橈動脈壓力諧波振幅,腦分支流阻變化的影響最大,其次是肝和腎,而胃腸脾的影響很小?梢,該模擬研究方法可以得到人體血流動力學(xué)參數(shù)與各器官流阻變化之間的理論聯(lián)系,為中醫(yī)脈診提供一些理論依據(jù)。
[Abstract]:Based on the principle of TCM, influence of the change of flow resistance on the hemodynamic parameters of each organ of the human body. The body circulation fluid network model of human body was established, and the expression of 10 harmonic hemodynamic expressions was used to simulate the cardiac output. Changes in various organs of flow resistance, flow resistance ratio is 0.5 and 1 respectively, 1.5, 2, 2.5, 3, using the average method to solve the model. Assuming the cardiac output, the results show that with the increase of flow resistance of the corresponding branch flow decreased; different branch flow resistance increase can cause the mean aortic pressure increases, when the ratio of =3.0 flow resistance, brain, liver, kidney, stomach, intestine, spleen branch flow resistance increase caused by aortic pressure than the normal value increased 23.29%, respectively 16.42%, 14.67%, 9.69%, 9.59%, 7.82%; liver and kidney branch flow resistance change has great influence on the radial artery, when the ratio of =3.0 flow resistance, radial artery pressure than normal values were increased by 22.85% and 11.17%, and other organs branch flow resistance change influence on the radial artery is small; the radial artery pressure harmonic amplitude. Effect of brain impedance branch flow is the largest, followed by liver and kidney, but have little influence of gastrointestinal spleen. Therefore, the method can get the simulation theory with human blood dynamics parameters and flow resistance change between different organs, provide some theoretical basis for tcm.
【作者單位】: 重慶大學(xué)動力工程學(xué)院低品位能源利用技術(shù)及系統(tǒng)教育部重點(diǎn)實(shí)驗(yàn)室;
【分類號】:O35;R241
【正文快照】: 引言流體網(wǎng)絡(luò)分析在很多領(lǐng)域中都有廣泛應(yīng)用。在生物動力學(xué)領(lǐng)域中,人體血液循環(huán)系統(tǒng)是一種周期性受迫的復(fù)雜流體網(wǎng)絡(luò),通過對其建模,可以得到血液流量、壓力等血流動力學(xué)參數(shù)。在人體血液循環(huán)系統(tǒng)建模中,主要采用電路網(wǎng)絡(luò)模擬和流體網(wǎng)絡(luò)解算兩種方法,而早期研究采用電路網(wǎng)絡(luò)模
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