【摘要】：有絲分裂災(zāi)難是一種新的細胞死亡形式,是有絲分裂過程失調(diào)而發(fā)生的細胞死亡現(xiàn)象,是一個真正意義上的內(nèi)源性腫瘤抑制機制。然而,盡管有絲分裂災(zāi)難在預(yù)防和治療腫瘤中具有重要意義,但其發(fā)生的分子機制尚未清晰闡明。本文探討腫瘤細胞發(fā)生有絲分裂災(zāi)難機制最新的研究進展,為腫瘤細胞發(fā)生有絲分裂災(zāi)難機制的進一步研究提供參考依據(jù)。
[Abstract]:Mitotic disaster is a new form of cell death, which is a phenomenon of cell death caused by the disorder of mitosis process, and it is a real mechanism of endogenous tumor inhibition. However, although mitotic disaster is of great significance in the prevention and treatment of tumors, the molecular mechanism of mitosis has not been clearly clarified. In this paper, the latest research progress on the mechanism of mitosis disaster in tumor cells is discussed, which provides a reference for the further study of the mechanism of mitosis disaster in tumor cells.
【作者單位】： 哈爾濱商業(yè)大學(xué)教育部抗腫瘤天然藥物工程研究中心;哈爾濱商業(yè)大學(xué)藥學(xué)院;哈爾濱商業(yè)大學(xué)藥物研究所博士后科研工作站;
【基金】：國家自然科學(xué)基金青年基金資助項目(81102858) 黑龍江省普通本科高等學(xué)校青年創(chuàng)新人才培養(yǎng)計劃基金資助項目(UNPYSCT-2015070) 黑龍江省博士后科研啟動基金資助項目(LBH-Q16130)
【分類號】：R73-3
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本文編號：2525198