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嬰兒血管瘤及血管畸形臨床分析

發(fā)布時間:2019-03-03 16:59
【摘要】:目的通過對大樣本嬰兒血管瘤及血管畸形相關臨床資料進行詳細統(tǒng)計分析,結合該類疾病相關文獻,掌握嬰兒血管瘤及血管畸形的發(fā)生、演變特點,指導該類疾病的臨床診治。研究對象及方法研究對象:2014年9月-2016年9月重慶醫(yī)科大學附屬兒童醫(yī)院血管瘤專科門診接診的2563例嬰兒血管瘤及血管畸形患者。研究方法:設計嬰兒血管瘤及血管畸形統(tǒng)計表,對首次就診時確診為嬰兒血管瘤及血管畸形患者相關臨床資料,包括患者性別、發(fā)病及就診年齡、病變分類、大小分型、病變部位、生長情況、相關并發(fā)癥、是否早產(chǎn)、家庭住址等按所設計的統(tǒng)計表進行詳細記錄,利用spss17.0統(tǒng)計軟件統(tǒng)計,分析各項資料的構成百分比及相互之間的關系。結果2150例嬰兒血管瘤,血管瘤2450個,女性患兒1436例,男性患兒714例,男女發(fā)病比例為1:2;血管畸形女性患兒220例,男性患兒193例,比例為1.12:1;嬰兒血管瘤出生時即出現(xiàn)病變者1206個,占41.9%,1月內出現(xiàn)者1944個,占79.35%,3月以上出現(xiàn)病變患兒71個,僅占2.9%;1853個于半歲內就診,占75.7%,1歲以上首次就診者103個,占4.2%;血管畸形首次就診年齡無明顯特點,各年齡段均有就診;嬰兒血管瘤病變類型以表淺型血管瘤為主,1740個,占70.8%;血管畸形則以靜脈畸形為主,209個,占49.9%;嬰兒血管瘤發(fā)病部位以頭面頸及軀干為主,分別為1072個及760個,占43.8%和31.0%;血管畸形頭面頸發(fā)病率最高,共201個,占48.7%;嬰兒血管瘤首次就診時病變大小主要以中小型為主,2308個,占94%,大型及巨大型142個,僅占6%;血管畸形中小型284個,占68.5%,大型及巨大型130個,占31.5%;嬰兒血管瘤首次就診時1958個處于生長期,占79.92%,390個處于穩(wěn)定期,占15.92%,102個處于消退期,占4.19%;嬰兒血管瘤多發(fā)234例,占11%,血管畸形多發(fā)患兒僅3例;嬰兒血管瘤早產(chǎn)兒109例,占5%,血管畸形早產(chǎn)兒僅23例。結論嬰兒血管瘤男女發(fā)病率有顯著差異,發(fā)生、生長均具有明顯特點,可自行消退,就診年齡亦具有相應特點,治療上可根據(jù)具體情況進行選擇;血管畸形生后即存在,生長緩慢,部分患兒就診較晚,導致病變較大,增加了治療難度;故在治療上建議早期進行干預。
[Abstract]:Objective to analyze the clinical data of large samples of infantile hemangioma and vascular malformations, and to understand the occurrence and evolution characteristics of hemangioma and vascular malformations in infants, so as to guide the clinical diagnosis and treatment of these diseases. Participants and methods: from September 2014 to September 2016, 2563 cases of infantile hemangioma and vascular malformations were treated in the out-patient clinic of hemangioma, affiliated Children's Hospital of Chongqing Medical University. Methods: to design the statistical tables of hemangioma and vascular malformation in infants, and to analyze the clinical data of the patients diagnosed as hemangioma and vascular malformation at the first visit, including the sex of the patient, the onset and age of the patient, the classification of the lesion, and the classification of the size of the disease. The lesion site, growth condition, related complications, preterm birth, family address and so on were recorded in detail according to the designed statistical tables, and the percentage of each data and the relationship between them were analyzed by using spss17.0 statistical software. Results 2150 cases of infantile hemangioma, 2450 hemangioma, 1436 female and 714 male, the ratio of male to female was 1-2, the ratio of female to male was 1.12%, the ratio of female to female was 1.12%, and the ratio of female to male was 1.12%. There were 1206 cases (41.9%) of hemangioma at birth, 1944 cases (79.35%) occurred within 1 month, 71 cases (2.9%) appeared more than 3 months after birth. 1853 patients (75.7%) were in the first visit within the age of half year, and over one year old (4.2%), there was no significant difference in the age of the first visit of vascular malformations, and all the age groups were found to be in the first visit. The main types of hemangioma in infants were superficial hemangiomas (1740, 70.8%), venous malformations (49.9%), venous malformations (70.8%) and venous malformations (49.9%). The main sites of infantile hemangioma were head, face, neck and torso, accounting for 43.8% and 31.0%, respectively, and the incidence of vascular malformations was the highest (48.7%, 48.7%), and the incidence of vascular malformations was the highest (48.7%). The size of hemangioma in infants was mainly small and medium size (94%), large and giant (6%), vascular malformations (68.5%), large and giant (31.5%), small and medium size (68.5%), large and giant (31.5%), small and medium size (68.5%), large and giant (31.5%). 1958 hemangiomas were in the growth phase (79.92%), stable phase (15.92%) and receding stage (4.19%). There were 234 cases (11%) with multiple hemangiomas, 3 cases with multiple vascular malformations, 109 cases (5%) with hemangioma and 23 cases with vascular malformations. Conclusion there is a significant difference in the incidence of hemangioma between males and females. The growth of hemangioma is characterized by its own regression and age of treatment. The treatment can be selected according to the specific conditions. Vascular malformations exist immediately after birth, grow slowly, and some children come to hospital later, which leads to large pathological changes and increases the difficulty of treatment. Therefore, early intervention is recommended in the treatment of vascular malformations.
【學位授予單位】:重慶醫(yī)科大學
【學位級別】:碩士
【學位授予年份】:2017
【分類號】:R732.2

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