發(fā)布時(shí)間：2019-01-30 14:16

【摘要】：目的:通過(guò)中醫(yī)體質(zhì)調(diào)查,統(tǒng)計(jì)分析甲狀腺乳頭狀癌患者的中醫(yī)體質(zhì)分布特征,探討其人口社會(huì)學(xué)特征;從中醫(yī)體質(zhì)學(xué)角度探討甲狀腺乳頭狀癌頸部淋巴結(jié)轉(zhuǎn)移的相關(guān)因素,為該病的防治研究提供臨床資料及參考。方法:采用問(wèn)卷調(diào)查形式獲取甲狀腺乳頭狀癌患者的中醫(yī)體質(zhì)分型,收集患者一般資料及頸部淋巴結(jié)轉(zhuǎn)移情況資料,以EXCEL建立數(shù)據(jù)庫(kù)并使用SPSS18.0統(tǒng)計(jì)軟件包分析中醫(yī)體質(zhì)的分布規(guī)律,分析其與一般資料及頸部淋巴結(jié)轉(zhuǎn)移情況的相關(guān)性。成果:1.119例甲狀腺乳頭狀癌患者中體質(zhì)為平和質(zhì)的有23例,占19.3%,偏頗體質(zhì)96例,占80.7%。與一般人群相比,差異具有統(tǒng)計(jì)學(xué)意義(P=0.00)。體質(zhì)類(lèi)型以單一體質(zhì)多見(jiàn),共93例,占78.2%,兼夾型體質(zhì)26例,占21.8%。單一型體質(zhì)中,占比重較大的前五類(lèi)體質(zhì)為平和質(zhì)23例(19.3%)、氣郁質(zhì)22例(18.5%)、陽(yáng)虛質(zhì)10例(8.4%)、陰虛質(zhì)10例(8.4%)、痰濕質(zhì)8例(6.7%)。兼夾體質(zhì)類(lèi)中兼夾2種體質(zhì)的22例,兼夾3種體質(zhì)4例,未見(jiàn)兼夾4種及以上的兼夾體質(zhì)類(lèi)型。在各型單一型體質(zhì)中,尚會(huì)出現(xiàn)傾向型體質(zhì)40例,以傾向氣郁質(zhì)、血瘀質(zhì)及痰濕質(zhì)型居多。2.關(guān)于不同頸部淋巴結(jié)轉(zhuǎn)移區(qū)域中,僅中央?yún)^(qū)轉(zhuǎn)移組平和質(zhì)7例,氣虛質(zhì)2例,陽(yáng)虛質(zhì)3例,陰虛質(zhì)4例,痰濕質(zhì)6例,濕熱質(zhì)2例,血瘀質(zhì)0例,氣郁質(zhì)9例,特稟質(zhì)0例,兼夾體質(zhì)12例;轉(zhuǎn)移至側(cè)區(qū)組平和質(zhì)7例,氣虛質(zhì)1例,陽(yáng)虛質(zhì)2例,陰虛質(zhì)1例,痰濕質(zhì)2例,濕熱質(zhì)2例,血瘀質(zhì)3例,氣郁質(zhì)6例,特稟質(zhì)1例,兼夾體質(zhì)7例。兩組差異無(wú)統(tǒng)計(jì)學(xué)意義(P=0.566)。3.關(guān)于淋巴結(jié)轉(zhuǎn)移組與無(wú)淋巴結(jié)轉(zhuǎn)移組兩組,頸部淋巴結(jié)轉(zhuǎn)移組平和質(zhì)14例,氣虛質(zhì)3例,陽(yáng)虛質(zhì)5例,陰虛質(zhì)5例,痰濕質(zhì)8例,濕熱質(zhì)4例,血瘀質(zhì)3例,氣郁質(zhì)15例,特稟質(zhì)1例,兼夾體質(zhì)19例;無(wú)頸部淋巴結(jié)轉(zhuǎn)移組平和質(zhì)9例,氣虛質(zhì)2例,陽(yáng)虛質(zhì)5例,陰虛質(zhì)5例,痰濕質(zhì)0例,濕熱質(zhì)3例,血瘀質(zhì)3例,氣郁質(zhì)7例,特稟質(zhì)1例,兼夾體質(zhì)7例。兩組差異無(wú)統(tǒng)計(jì)學(xué)意義(P=0.391)。結(jié)論:1.甲狀腺乳頭狀癌患者中醫(yī)體質(zhì)分布與一般人群體質(zhì)分布存在差異,偏頗體質(zhì)比例較一般人群高,提示偏頗體質(zhì)與甲狀腺乳頭狀癌的發(fā)病具有相關(guān)性。2.甲狀腺乳頭狀癌患者中醫(yī)體質(zhì)類(lèi)型以偏頗體質(zhì)為主,其中兼夾體質(zhì)多見(jiàn)。偏頗體質(zhì)中單一型體質(zhì)較多見(jiàn)的為氣郁質(zhì)、陽(yáng)虛質(zhì)、陰虛質(zhì)以及痰濕質(zhì)。3.本研究結(jié)果提示中醫(yī)體質(zhì)分布與頸部淋巴結(jié)轉(zhuǎn)移之間未見(jiàn)明顯統(tǒng)計(jì)學(xué)差異,可能提示體質(zhì)與甲狀腺乳頭狀癌頸部淋巴結(jié)轉(zhuǎn)移無(wú)明顯相關(guān)性,或存在一定相關(guān)性,但由于時(shí)間有限,樣本量不足導(dǎo)致未能出現(xiàn)明顯統(tǒng)計(jì)學(xué)差異。
[Abstract]:Objective: to analyze the distribution of TCM constitution in patients with papillary thyroid carcinoma and to explore its demographic and sociological characteristics. To explore the related factors of cervical lymph node metastasis in papillary thyroid carcinoma from the perspective of TCM physique, and to provide clinical data and reference for the prevention and treatment of the disease. Methods: the TCM constitution classification of patients with papillary thyroid carcinoma was obtained by questionnaire, and the general data of patients and the status of cervical lymph node metastasis were collected. The database was established by EXCEL and the distribution law of TCM constitution was analyzed by SPSS18.0 software package. The correlation between the data and general data and cervical lymph node metastasis was analyzed. Results: among 1.119 patients with papillary thyroid carcinoma, 23 cases (19.3%) had mild constitution, 96 cases (80.7%) had partial constitution. Compared with the general population, the difference was statistically significant (P0. 00). There were 93 cases (78.2%) with single constitution and 26 cases (21.88%) with clip constitution. In the single type of constitution, 23 cases (19.3%) were mild type, 22 cases (18.5%) were qi stagnation, 10 cases (8.4%) were yang deficiency, 10 cases (8.4%) were yin deficiency. Phlegm dampness in 8 cases (6.7%). There were 22 cases of two kinds of constitution and 4 cases of 3 kinds of constitution in the category of concurrent clamping constitution, but there was no type of concurrent clamping constitution of 4 or more kinds of concurrently clamping constitution. Among the single types of physique, there were 40 cases of inclined constitution, most of which were inclined to qi stagnation, blood stasis and phlegm dampness. In different cervical lymph node metastases, there were only 7 cases of calmness, 2 cases of qi deficiency, 3 cases of yang deficiency, 4 cases of yin deficiency, 6 cases of phlegm and dampness, 2 cases of dampness and heat, 0 cases of blood stasis, 9 cases of qi stagnation and 0 cases of intrinsic substance. 12 cases were also clamped; There were 7 cases of calmness, 1 case of qi deficiency, 2 cases of yang deficiency, 1 case of yin deficiency, 2 cases of phlegm and dampness, 2 cases of dampness and heat, 3 cases of blood stasis, 6 cases of qi stagnation, 1 case of intrinsic substance and 7 cases of inclusion constitution. There was no significant difference between the two groups (P < 0. 566). There were 14 cases of cervical lymph node metastasis, 3 cases of qi deficiency, 5 cases of yang deficiency, 5 cases of yin deficiency, 8 cases of phlegm and dampness, 4 cases of dampness and heat, 3 cases of blood stasis and 15 cases of qi stagnation. 1 case was idiosyncratic, and 19 cases were clamping constitution; In the group without cervical lymph node metastasis, 9 cases were mild, 2 cases were qi deficiency, 5 cases were yang deficiency, 5 cases were yin deficiency, 0 cases were phlegm dampness, 3 cases were damp heat, 3 cases were blood stasis, 7 cases were qi stagnation, 1 case was intrinsic substance, and 7 cases were clamping constitution. There was no significant difference between the two groups (P = 0.391). Conclusion: 1. The physique distribution of traditional Chinese medicine in patients with thyroid papillary carcinoma was different from that of the general population, and the proportion of biased constitution was higher than that of the general population, suggesting that biased constitution had a correlation with the incidence of papillary thyroid carcinoma. 2. The traditional Chinese medicine constitution type of thyroid papillary carcinoma is biased constitution. Biased physique in the single type of physique is more common for Qi stagnation, Yang deficiency, Yin deficiency and phlegm dampness. 3. The results of this study suggest that there is no significant statistical difference between TCM constitution distribution and cervical lymph node metastasis, and there may be no significant correlation between constitution and cervical lymph node metastasis of papillary thyroid carcinoma, or there is a certain correlation between constitution and cervical lymph node metastasis. However, due to limited time and insufficient sample size, there was no significant statistical difference.
【學(xué)位授予單位】：廣州中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類(lèi)號(hào)】：R736.1

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 閆維;姜濤;鄭曉;;甲狀腺乳頭狀癌頸淋巴結(jié)轉(zhuǎn)移特點(diǎn)及危險(xiǎn)因素分析[J];現(xiàn)代腫瘤醫(yī)學(xué);2017年05期

2 翟寶偉;高慶軍;趙代偉;;甲狀腺微小乳頭狀癌頸部淋巴結(jié)轉(zhuǎn)移的危險(xiǎn)因素分析[J];中國(guó)普通外科雜志;2016年11期

3 韓靚;蔣斌;徐新江;湯明明;季振華;戴文成;;多灶性甲狀腺癌的危險(xiǎn)因素評(píng)估和治療策略[J];中國(guó)眼耳鼻喉科雜志;2016年05期

4 王小龍;高天舒;;甲狀腺功能正常橋本甲狀腺炎患者中醫(yī)體質(zhì)特征調(diào)查[J];北京中醫(yī)藥;2016年06期

5 譚卓;聶喜林;鄭傳銘;蔣烈浩;葛明華;王佳峰;;甲狀腺微小乳頭狀癌側(cè)頸部淋巴結(jié)轉(zhuǎn)移相關(guān)危險(xiǎn)因素分析[J];浙江醫(yī)學(xué);2016年11期

6 陳萬(wàn)青;鄭榮壽;張思維;曾紅梅;左婷婷;賈漫漫;夏昌發(fā);鄒小農(nóng);赫捷;;2012年中國(guó)惡性腫瘤發(fā)病和死亡分析[J];中國(guó)腫瘤;2016年01期

7 王娜;毛德文;陳小明;龍富立;唐農(nóng);;205例廣西乙型肝炎肝硬化患者的中醫(yī)體質(zhì)規(guī)律研究[J];中國(guó)醫(yī)藥導(dǎo)報(bào);2015年10期

8 李小燕;郭世俊;李春霖;;原發(fā)性高血壓合并高尿酸血癥患者的中醫(yī)體質(zhì)特點(diǎn)[J];廣東醫(yī)學(xué);2015年06期

9 毛露鳳;陳培豐;;陳培豐教授從氣論治甲狀腺癌經(jīng)驗(yàn)[J];浙江中西醫(yī)結(jié)合雜志;2015年01期

10 楊進(jìn)寶;李小毅;商中華;;甲狀腺乳頭狀癌各亞型臨床病理特點(diǎn)的研究進(jìn)展[J];癌癥進(jìn)展;2015年01期

相關(guān)會(huì)議論文 前1條

1 俞欣瑋;劉蕊;;甲狀腺癌術(shù)后中醫(yī)藥康復(fù)的優(yōu)勢(shì)[A];中華中醫(yī)藥學(xué)會(huì)中醫(yī)藥傳承創(chuàng)新與發(fā)展研討會(huì)專(zhuān)輯[C];2007年

，

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