【摘要】：目的探討肺癌術(shù)后發(fā)生下肢深靜脈血栓(LEDVT)的主要危險因素。方法采用非隨機同期對照研究方法,收集2013年3月至2015年12月在吉林大學(xué)第一醫(yī)院胸外科收入院并施行手術(shù)治療的肺癌患者108例,分為肺癌術(shù)后伴發(fā)LEDVT組36例和對照組72例,比較兩組性別、年齡、體重指數(shù)(BMI)、是否患糖尿病、化療情況、腫瘤分期、腫瘤病理類型以及手術(shù)方式、手術(shù)時間、術(shù)中出血情況等多種因素。結(jié)果兩組術(shù)后是否合并2型糖尿病(T2DM)、術(shù)前是否行化療、肺癌病理類型、肺癌分期、手術(shù)方式、手術(shù)時間等比較有統(tǒng)計學(xué)意義(P0.05)。Logistic二元回歸分析提示肺癌病理類型、肺癌分期、手術(shù)方式等因素與肺癌術(shù)后LEDVT發(fā)生密切相關(guān)(OR=2.307、3.105、2.102)。結(jié)論肺腺癌、肺癌Ⅲ期、開胸手術(shù)是肺癌術(shù)后形成LEDVT的獨立危險因素;肺癌患者在術(shù)前應(yīng)評估發(fā)生LEDVT的風(fēng)險,以期能早期預(yù)防、早期診斷,早期治療,從而降低肺癌患者術(shù)后發(fā)生LEDVT的概率。
[Abstract]:Objective to investigate the main risk factors of (LEDVT) in lower extremity deep vein thrombosis after lung cancer operation. Methods from March 2013 to December 2015, 108 patients with lung cancer received surgical treatment in Department of Thoracic surgery, first Hospital of Jilin University, were divided into 36 patients with postoperative lung cancer associated with LEDVT and 72 patients in control group. The sex, age, body mass index (BMI),) of the two groups were compared for diabetes mellitus, chemotherapy, tumor staging, tumor pathological type, operation mode, operation time, intraoperative bleeding and so on. Results there were two groups: type 2 diabetes mellitus (T2DM), preoperative chemotherapy, pathological type of lung cancer, stage of lung cancer, operation mode. The time of operation was statistically significant (P0.05). Logistic binary regression analysis showed that lung cancer pathological type, lung cancer staging, surgical methods and other factors are closely related to the incidence of LEDVT (OR=2.307,3.105,2.102). Conclusion Lung adenocarcinoma, stage 鈪，

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