放大內(nèi)鏡聯(lián)合窄帶成像在胃部早期腫瘤性病變患者中的應(yīng)用效果
[Abstract]:Objective to evaluate the effect of magnifying endoscopy combined with narrow band imaging (ME-NBI) in patients with early gastric neoplasms. Methods 151 patients with suspected early gastric cancer who underwent endoscopy from January 2013 to June 2016 were selected as study subjects. All patients were examined by ordinary white light endoscopy (WLE), then by ME-NBI and targeted biopsy. The interstitial distance of glandular tubules (hereinafter referred to as glandular spacing) was measured and divided into early carcinoma group [high grade intraepithelial neoplasia (HGIN), intramucosal carcinoma, submucosal carcinoma, nongma 72] and non-early carcinoma group [low grade intraepithelial neoplasia (LGIN), nm79] according to pathological results. The baseline data and ME-NBI signs were compared between the two groups. The area (AUC) under the operating curve was used to evaluate the diagnostic value of the two groups for early gastric carcinoma. Results the incidence of increased border, irregular mucosal microvessels, irregular surface glandular tube and glandular spacing in early cancer group was significantly higher than that in non-early cancer group (P0.05). The AUC of ME-NBI for gastric early carcinoma was 0.947. The sensitivity of (Sp), positive predictive value of (Se), specificity was higher than that of WLE 0.832. The predictive value of (PPV), negative predictive value and Youden index of (PPV), negative predictive value were 97.2% and 84.8%, respectively. 97.1% and 0.820%. The AUC of glandular spacing for early gastric carcinoma was 0.907, which was higher than that of traditional microvascular texture and surface structure (VS) typing. The AUC of VS classification combined with glandular spacing was 0.933, and its Se,Sp,PPV, was higher than that of traditional microvascular texture and surface structure (VS) typing. The NPV and Youden indexes were 95.83.5and 84.1percent, respectively. Conclusion ME-NBI is an important method for the diagnosis of early gastric carcinoma. The interglandular spacing has the advantages of objectivity, simplicity and reproducibility. It can assist the traditional VS classification to judge the nature of the lesions.
【作者單位】： 浙江省麗水市中心醫(yī)院體檢中心;浙江省麗水市中心醫(yī)院門(mén)診部;浙江省麗水市中心醫(yī)院消化內(nèi)科;
【分類號(hào)】：R735.2
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