【摘要】：近年來(lái)發(fā)現(xiàn),JAK2-STAT3信號(hào)通路參與腫瘤細(xì)胞的生長(zhǎng)、增殖、分化、轉(zhuǎn)移、凋亡。在肝細(xì)胞癌(HCC)細(xì)胞中的JAK蛋白和STAT蛋白過(guò)表達(dá),JAK2-STAT3信號(hào)通路與HCC發(fā)生發(fā)展密切相關(guān)。筆者就JAK2-STAT3信號(hào)通路在HCC的研究進(jìn)展做一綜述。
[Abstract]:In recent years, JAK2-STAT3 signaling pathway has been found to be involved in the growth, proliferation, differentiation, metastasis and apoptosis of tumor cells. Overexpression of JAK protein and STAT protein in hepatocellular carcinoma (HCC) cells, JAK2-STAT3 signaling pathway is closely related to the occurrence and development of HCC. This paper reviews the research progress of JAK2-STAT3 signaling pathway in HCC.
【作者單位】： 中南大學(xué)湘雅醫(yī)院衛(wèi)生部納米生物技術(shù)重點(diǎn)實(shí)驗(yàn)室;
【基金】：國(guó)家自然科學(xué)基金資助項(xiàng)目(81302075,81272193,81402001)
【分類號(hào)】：R735.7

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本文編號(hào)：2350178