不同分子亞型乳腺癌骨轉(zhuǎn)移患者的臨床特征和預(yù)后分析
[Abstract]:Objective to investigate the clinicopathological features and prognosis of different molecular subtypes of breast cancer with bone metastasis. Methods from September 1, 2007 to September 1, 2011, 300 patients with bone metastasis from breast cancer were collected from the first affiliated Hospital of Xi'an Jiaotong University, and their clinical features and prognosis were analyzed retrospectively. Results the percentage of Luminal A type, Luminal B, Her-2 overexpression type and triple negative breast cancer in this group was 59.016.0% and 11.3.4%, respectively. The difference of primary tumor size and histological grade was statistically significant (P0.05), but menopausal status, lymph node metastasis, Kaplan-Meier survival analysis showed that the median survival time of patients with bone metastasis of, Luminal A breast cancer was 28.6 months, which was higher than that of Luminal B patients (26.9 months). Her-2 overexpression (20.9 months) and three-negative (12.0 months) breast cancer bone metastasis patients. 4 groups of patients with total survival time difference was statistically significant (P0.05). Conclusion the clinical features and prognosis of patients with bone metastases from breast cancer with different subtypes are different. The prognosis of patients with bone metastasis of; Lumina A type breast cancer is better than that of patients with bone metastasis of triple negative breast cancer.
【作者單位】: 西安交通大學(xué)第一附屬醫(yī)院腫瘤內(nèi)科;
【分類號】:R737.9
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